mifepristone - Generic Medications

KORLYM (mifepristone) is a cortisol receptor blocker for oral administration. The chemical name of mifepristone is 11β-(4-dimethylaminophenyl)-17β-hydroxy-17α-(1-propynyl)-estra-4, 9-dien-3-one. The chemical formula is C 29 H 35 NO 2 ; the molecular weight is 429.60, and the structural formula is: Mifepristone demonstrates a pH-related solubility profile. The greatest solubility is achieved in acidic media (~ 25 mg/mL at pH 1.5) and solubility declines rapidly as the pH is increased. At pH values above 2.5 the solubility of mifepristone is less than 1 mg/mL. Each KORLYM tablet for oral use contains 300 mg of mifepristone. The inactive ingredients of KORLYM tablets are silicified microcrystalline cellulose, sodium starch glycolate, hydroxypropylcellulose, sodium lauryl sulfate, magnesium stearate, hypromellose, titanium dioxide, triacetin, D&C yellow 10 aluminum lake, polysorbate 80, and FD&C yellow 6 aluminum lake. Structural Formula

Mifepristone is a cortisol receptor blocker for oral administration. The chemical name of mifepristone is 11β-(4-dimethylaminophenyl)-17β-hydroxy-17α-(1-propynyl)-estra-4, 9-dien-3-one. The molecular formula is C 29 H 35 NO 2 ; the molecular weight is 429.60, and the structural formula is: Mifepristone demonstrates a pH-related solubility profile. The greatest solubility is achieved in acidic media (~ 25 mg/mL at pH 1.5) and solubility declines rapidly as the pH is increased. At pH values above 2.5 the solubility of mifepristone is less than 1 mg/mL. Each mifepristone tablet for oral use contains 300 mg of mifepristone. The inactive ingredients of mifepristone tablets are FD&C Blue #1 Brilliant Blue FCF Aluminum Lake, FD&C Yellow #5 (tartrazine) Aluminum Lake, FD&C Yellow #6 Sunset Yellow FCF Aluminum Lake, hydroxypropyl cellulose, hypromellose, magnesium stearate, polysorbate 80, microcrystalline cellulose, sodium lauryl sulfate, sodium starch glycolate type A, titanium dioxide, and triacetin. 1

Mifepristone tablets each contain 200 mg of mifepristone, a synthetic steroid with antiprogestational effects. The tablets are light yellow in color, circular, bi-convex, and are intended for oral administration only. The tablets include the inactive ingredients colloidal silicon dioxide, corn starch, povidone, microcrystalline cellulose, and magnesium stearate. Mifepristone is a substituted 19-nor steroid compound chemically designated as 11ß-[ p - (Dimethylamino) phenyl]-17ß-hydroxy- 17-(1-propynyl) estra-4,9-dien-3-one. Its empirical formula is C 29 H 35 NO 2 . Its structural formula is: The compound is a yellow powder with a molecular weight of 429.6 and a melting point of 192- 196°C. It is freely soluble in methanol, chloroform and acetone and poorly soluble in water, hexane and isopropyl ether. mifepristone-str

Mifepristone is a cortisol receptor blocker for oral administration. The chemical name of mifepristone is 11β-(4-dimethylaminophenyl)-17β-hydroxy-17α-(1-propynyl)-estra-4, 9-dien-3-one. The chemical formula is C 29 H 35 NO 2 ; the molecular weight is 429.60, and the structural formula is: Mifepristone demonstrates a pH-related solubility profile. The greatest solubility is achieved in acidic media (~ 25 mg/mL at pH 1.5) and solubility declines rapidly as the pH is increased. At pH values above 2.5 the solubility of mifepristone is less than 1 mg/mL. Each mifepristone tablet for oral use contains 300 mg of mifepristone. The inactive ingredients of mifepristone tablets are silicified microcrystalline cellulose, sodium starch glycolate, hydroxypropylcellulose, sodium lauryl sulfate, magnesium stearate, hypromellose, titanium dioxide, triacetin, D&C yellow 10 aluminum lake, polysorbate 80, and FD&C yellow 6 aluminum lake. Structural Formula

Mifepristone tablets each contain 200 mg of mifepristone, a synthetic steroid with antiprogestational effects. The tablets are light yellow coloured, round, biconvex, debossed with “CC12” on one side, plain on other side and free from physical defects and are intended for oral administration only. The tablets include the inactive ingredients colloidal silicon dioxide, maize starch, povidone, microcrystalline cellulose, and magnesium stearate. Mifepristone is a substituted 19-nor steroid compound chemically designated as 11ß-[ p - (Dimethylamino) phenyl]-17ß-hydroxy- 17-(1-propynyl) estra-4,9-dien-3-one. Its empirical formula is C 29 H 35 NO 2 . Its structural formula is: The compound is a yellow powder with a molecular weight of 429.6 and a melting point of 192 to 196°C. It is very soluble in methanol, chloroform and acetone and poorly soluble in water, hexane and isopropyl ether. structure