Drugs Similar to PHENYLEPHRINE HYDROCHLORIDE INJECTION, SOLUTION

Uses temporarily relieves nasal congestion due to: common cold hay fever upper respiratory allergies

Uses Temporarily relieves • nasal congestion due to the common cold, hay fever or other upper respiratory allergies • sinus congestion and pressure

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses for the temporary relief of nasal congestion due to: common cold hay fever upper respiratory allergies

Phenylephrine is an alpha-1 adrenergic receptor agonist. The chemical name of phenylephrine hydrochloride is (-)- m -hydroxy-α-[(methylamino) methyl] benzyl alcohol hydrochloride, its molecular formula is C 9 H 13 NO 2 · HCl (Molecular Weight: 203.67g/mol). Its structural formula is depicted below: Phenylephrine hydrochloride is soluble in water and ethanol, and insoluble in chloroform and ethyl ether. BIORPHEN Injection, 500 mcg/5 mL (100 mcg/mL): BIORPHEN (phenylephrine hydrochloride) injection, 500 mcg/5 mL (100 mcg/mL),, is a sterile, nonpyrogenic, clear and colorless solution for intravenous use. It MUST NOT BE DILUTED before administration as an intravenous bolus. Each mL contains: phenylephrine hydrochloride 100 mcg (equivalent to 80 mcg of phenylephrine base), sodium chloride 9.0 mg in water for injection. The pH is adjusted with hydrochloric acid if necessary. The pH range is 3.0 to 5.0. BIORPHEN Injection, 10 mg/mL: BIORPHEN (phenylephrine hydrochloride) injection, 10 mg/mL, is a sterile, nonpyrogenic, clear and colorless solution for intravenous use. It MUST BE DILUTED before administration as an intravenous bolus or continuous intravenous infusion. Each mL contains: phenylephrine hydrochloride 10 mg (equivalent to 8.2 mg of phenylephrine base), sodium chloride 6.0 mg in water for injection. The pH is adjusted with hydrochloric acid if necessary. The pH range is 3.0 to 5.0. Chemical Structure

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies temporarily relieves sinus congestion and pressure

Uses Temporarily relieves ■ nasal congestion due to the common cold, hay fever or other upper respiratory allergies ■ sinus congestion and pressure

Uses for the temporary relief of nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses temporarily relieves nasal congestion due to: •common cold •hay fever •upper respiratory allergies •temporarily relieves sinus congestion and pressure •shrinks swollen membranes so you can breathe more freely •temporarily restores freer breathing through the nose

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies • temporarily relieves sinus congestion and pressure • shrinks swollen nasal membranes so you can breathe more freely

Uses temporarily relieves nasal congestion due to: common cold hay fever upper respiratory allergies (allergic rhinitis) temporarily relieves sinus congestion and pressure shrinks swollen membranes so you can breathe more freely temporarily restores freer breathing through the nose

Uses temporarily relieves nasal congestion: due to common cold due to hay fever or other upper respiratory allergies (allergic rhinitis) temporarily relieves stuffy nose. helps clear nasal passages; shrinks swollen membranes temporarily restores freer breathing through the nose helps decongest sinus openings and passages; temporarily relieves sinus congestion and pressure

USES: temporarily relieves sinus congestion and pressure temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies

USES: temporarily relieves sinus congestion and pressure temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies

Uses for the temporarily relief of nasal congestion due to: common cold hay fever upper respiratory allergies

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies

Uses. Forthe temporany relief of local and anorectal iching and discomfot asociated with anoreclal isorders and anorectalimammation. Forthe temporany reief of pain,buring and sorenes. Temporarily shrinks hemorthoidal tisue, Temporarily reduces the sweling associated with iritation in hemorthoids and other anorectal disorders.

Uses temporarily relieves common cold/flu symptoms: cough due to minor throat & bronchial irritation sore throat headache minor aches & pains fever runny nose and sneezing

Omidria is a sterile aqueous solution, containing the α 1 -adrenergic receptor agonist phenylephrine HCl and the nonsteroidal anti-inflammatory ketorolac tromethamine, for addition to ocular irrigating solution. The descriptions and structural formulae are: Phenylephrine Hydrochloride Drug Substance: Common Name: phenylephrine hydrochloride Chemical Name: (-)- m -Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride Molecular Formula: C 9 H 13 NO 2 · HCl Molecular Weight: 203.67 g/mole Figure 1: Chemical Structure for Phenylephrine HCl Ketorolac Tromethamine Drug Substance: Common Name: ketorolac tromethamine Chemical Name: (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) Molecular Formula: C 15 H 13 NO 3 · C 4 H 11 NO 3 Molecular Weight: 376.40 g/mole Figure 2: Chemical Structure for Ketorolac Tromethamine Omidria is a clear, colorless to slightly yellow, sterile solution concentrate with a pH of approximately 6.3. Each vial of Omidria contains: Actives: phenylephrine hydrochloride 12.4 mg/mL equivalent to 10.16 mg/mL of phenylephrine and ketorolac tromethamine 4.24 mg/mL equivalent to 2.88 mg/mL of ketorolac. Inactives: citric acid monohydrate; sodium citrate dihydrate; water for injection; may include sodium hydroxide and/or hydrochloric acid for pH adjustment. Figure 1 Figure 2

Use temporarily relieves: headache sinus pain nasal and sinus congestion minor aches and pains fever

Use temporarily relieves: headache sinus pain nasal and sinus congestion minor aches and pains fever