Drugs Similar to NITROGLYCERIN IN DEXTROSE
NITROGLYCERIN DEXTROSE
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By Brand
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Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is whose empiric formula is C 3 H 5 N 3 O 9 , and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins. Dextrose (Dextrose Hydrous, USP) is D-glucose monohydrate, a hexose sugar whose structural formula is whose empiric formula is C 6 H 12 O 6 • H 2 O, and whose molecular weight is 198.17. Dextrose is derived from corn. Nitroglycerin in 5% Dextrose Injection is a sterile, nonpyrogenic solution of nitroglycerin and dextrose in water for injection. The solution is clear and practically colorless. Each 100 mL contains 10 mg, 20 mg, or 40 mg nitroglycerin (added as Diluted Nitroglycerin, USP with propylene glycol); 5 g Dextrose Hydrous, USP; 0.84 mL Alcohol, USP (added as a dissolution aid); and 105 mg Citric Acid Hydrous, USP (added as a buffer). The pH of the solution is adjusted with sodium hydroxide and, if necessary, hydrochloric acid. Although dry nitroglycerin is explosive, nitroglycerin in 5% dextrose is not. Composition, osmolarity and pH are given in Table 1. Table 1 Composition Normal physiologic osmolarity range is approximately 280 to 310 mOsmol/L. Administration of substantially hypertonic solutions (≥600 mOsmol/L) may cause vein damage. Osmolarity (mOsmol/L) (calc) pH Nitroglycerin (mcg/mL) Dextrose Hydrous, USP (g/L) 25 mg Nitroglycerin in 5% Dextrose Injection 100 50 428 4.0 (3.0 to 5.0) 50 mg Nitroglycerin in 5% Dextrose Injection 200 50 440 4.0 (3.0 to 5.0) 100 mg Nitroglycerin in 5% Dextrose Injection 400 50 465 4.0 (3.0 to 5.0) Nitroglycerin Structural Formula Dextrose Structural Formula
Nitroglycerin is 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is whose empiric formula is C 3 H 5 N 3 O 9 , and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins. Dextrose (Dextrose Hydrous, USP) is D-glucose monohydrate, a hexose sugar whose structural formula is whose empiric formula is C 6 H 12 O 6 • H 2 O, and whose molecular weight is 198.17. Dextrose is derived from corn. Nitroglycerin in 5% Dextrose Injection is a sterile, nonpyrogenic solution of nitroglycerin and dextrose in water for injection. The solution is clear and practically colorless. Each 100 mL contains 10 mg, 20 mg, or 40 mg nitroglycerin (added as Diluted Nitroglycerin, USP with propylene glycol); 5 g Dextrose Hydrous, USP; 0.84 mL Alcohol, USP (added as a dissolution aid); and 105 mg Citric Acid Hydrous, USP (added as a buffer). The pH of the solution is adjusted with sodium hydroxide and, if necessary, hydrochloric acid. Although dry nitroglycerin is explosive, nitroglycerin in 5% dextrose is not. Composition, osmolarity and pH are given in Table 1. Table 1 Composition Normal physiologic osmolarity range is approximately 280 to 310 mOsmol/L. Administration of substantially hypertonic solutions (≥600 mOsmol/L) may cause vein damage. Osmolarity (mOsmol/L) (calc) pH Nitroglycerin (mcg/mL) Dextrose Hydrous, USP (g/L) 25 mg Nitroglycerin in 5% Dextrose Injection 100 50 428 4.0 (3.0 to 5.0) 50 mg Nitroglycerin in 5% Dextrose Injection 200 50 440 4.0 (3.0 to 5.0) 100 mg Nitroglycerin in 5% Dextrose Injection 400 50 465 4.0 (3.0 to 5.0) Nitroglycerin Structural Formula Dextrose Structural Formula
By Substance
Drugs sharing the same substance name
INDICATIONS For temporary relief of anxiousness, stress, or excessive worry or emotion.*
INDICATIONS For the temporary relief of muscle cramps or spasms, muscular debility, mild abdominal, back or chest pain, or anxiousness.*
INDICATIONS For the temporary relief of weakness, exhaustion, restlessness, anxiousness, or muscle pain, spasms, or tightness.*
INDICATIONS AND USAGE: For temporary relief of numbness, tingling, discoloration, coldness, and burning of the lower extremities.
INDICATIONS AND USAGE For temporary relief of numbness, tingling, discoloration, coldness, and burning of the lower extremities.
USES: For temporary relief of heaviness, tiredness after minimal exercise, difficulty breathing after exercise.
INDICATIONS: For temporary relief of heaviness, tiredness after minimal exercise, difficulty breathing after exercise.
INDICATIONS: May temporarily relieve symptoms of swollen extremities, bruised feeling, cold clammy feet, mild burning pains in leg, and weakness in limbs.** **Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.
Uses Temporarily relieves discomfort due to blood pressure issues, including occasional dizziness, headaches, and blurred vision.* *CLAIMS BASED ON TRADITIONAL HOMEOPATHIC PRACTICE, NOT ACCEPTED MEDICAL EVIDENCE, NOT FDA EVALUATED. This product is not intended to diagnose, treat, cure, or prevent any disease.
Uses Temporarily relieves occasional chest discomfort, discomfort radiating to the arms, neck, jaw, and upper abdomen, and intense emotions.*
Indications & dosage: Referred to enclosed self help guide or as advised by a homoeopathic physician.
USES; • For the temporary relief of symptoms including: • headache • fatigue • confusion • intimacy issues These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.
USES: • For the temporary relief of symptoms including: • headache • fatigue • confusion • intimacy issues These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.
INDICATIONS For the temporary relief of muscle cramps or spasms, mild abdominal or chest pain, or anxiousness.*
INDICATIONS & USAGE SECTION Formulated for symptoms such as fear, cold hands & feet, headache, weakness, sallow skin and palpitations.
INDICATIONS: For temporary relief of heaviness of the chest, tiredness after minimal exercise, difficulty breathing with heaviness.
INDICATIONS: For temporary relief of heaviness of the chest, tiredness after minimal exercise, difficulty breathing with heaviness.
INDICATIONS: May temporarily relieve weakness and exhaustion, minor abdominal cramps, bloating, and vomiting.** **Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.
USES: • For the temporary relief of symptoms including: • circulation support • exhaustion These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.
INDICATIONS & USAGE SECTION Formulated for associated symptoms such as dizziness, fatigue, weakness, tingling and numb or cold extremities.