Cold and Flu Nighttime ACETAMINOPHEN DEXTROMETHORPHAN HBR TRIPROLIDINE HCL CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED FDA Approved Uses temporarily relieves these common cold and flu symptoms: headache minor aches and pains sneezing runny nose itching of the nose or throat cough sore throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep
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Substance Acetaminophen
Route
ORAL
Applications
M012
Package NDC

Drug Facts

Composition & Profile

Active Ingredients
Active ingredients (in each 20 mL) Acetaminophen 650 mg Dextromethorphan HBr 20 mg Triprolidine HCl 2.5 mg
Inactive Ingredients
Inactive ingredients anhydrous citric acid FD&C blue #1 FD&C red #40 FD&C yellow #6 flavors glycerin propylene glycol purified water sodium benzoate sucralose xanthan gum
Strengths
20 ml 650 mg 20 mg 2.5 mg
Quantities
177 ml
Treats Conditions
Uses Temporarily Relieves These Common Cold And Flu Symptoms Headache Minor Aches And Pains Sneezing Runny Nose Itching Of The Nose Or Throat Cough Sore Throat Itchy Watery Eyes Due To Hay Fever Temporarily Reduces Fever Controls Cough To Help You Get To Sleep
Pill Appearance
Color: blue

Identifiers & Packaging

Container Type UNKNOWN
All Product Codes
UNII
362O9ITL9D 9D2RTI9KYH YAN7R5L890
Packaging

Principal Display Panel 51316-963-45 ♥CVS ™ NIGHTTIME COLD & FLU ACETAMINOPHEN Pain Reliever, Fever Reducer Dextromethorphan HBr Cough Suppressant Triprolidine HCl, Antihistamine Compare to Mucinex® Nightshift™ Cold & Flu active ingredients* Relieves: Fever & sore throat, Runny nose, Sneezing Controls Cough 6 FL OZ (177 mL) | Ages 12 & Older TAMPER EVIDENT: DO NOT USE IF IMPRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING PARENTS: Learn about teen medicine abuse www.StopMedicineAbuse.org *This product is not manufactured or distributed by RB Health (US) LLC, owner of the registered trademark Mucinex® Nightshift™ Cold & Flu. B-063-45 ORG 50844 ORG072406345 Distributed by: CVS Pharmacy, Inc. One CVS Drive Woonsocket, RI 02895 © 2025 CVS/pharmacy CVS.com® 1-800-SHOP CVS V-19849 CVS 44-063 CVS 44-063

Package Descriptions
  • Principal Display Panel 51316-963-45 ♥CVS ™ NIGHTTIME COLD & FLU ACETAMINOPHEN Pain Reliever, Fever Reducer Dextromethorphan HBr Cough Suppressant Triprolidine HCl, Antihistamine Compare to Mucinex® Nightshift™ Cold & Flu active ingredients* Relieves: Fever & sore throat, Runny nose, Sneezing Controls Cough 6 FL OZ (177 mL) | Ages 12 & Older TAMPER EVIDENT: DO NOT USE IF IMPRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING PARENTS: Learn about teen medicine abuse www.StopMedicineAbuse.org *This product is not manufactured or distributed by RB Health (US) LLC, owner of the registered trademark Mucinex® Nightshift™ Cold & Flu. B-063-45 ORG 50844 ORG072406345 Distributed by: CVS Pharmacy, Inc. One CVS Drive Woonsocket, RI 02895 © 2025 CVS/pharmacy CVS.com® 1-800-SHOP CVS V-19849 CVS 44-063 CVS 44-063

Overview

Uses temporarily relieves these common cold and flu symptoms: headache minor aches and pains sneezing runny nose itching of the nose or throat cough sore throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep

Indications & Usage

Uses temporarily relieves these common cold and flu symptoms: headache minor aches and pains sneezing runny nose itching of the nose or throat cough sore throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep

Dosage & Administration

Directions do not take more than directed do not take more than 4 doses in any 24-hour period mL = milliliter only use the dose cup provided adults and children 12 years and over: 20 mL in dosing cup provided every 4 hours children under 12 years: do not use

Warnings & Precautions
Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take 3 or more alcoholic drinks every day while using this product more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: rash blisters skin reddening If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have cough that occurs with too much phlegm (mucus) difficulty in urination due to enlargement of the prostate gland liver disease a breathing problem such as emphysema or chronic bronchitis glaucoma persistent or chronic cough such as occurs with smoking, asthma, or emphysema Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin When using this product excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness marked drowsiness may occur use caution when driving a motor vehicle or operating machinery avoid alcoholic beverages Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Purpose

Purpose Pain reliever/fever reducer Cough suppressant Antihistamine

Do Not Use

Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

When Using

When using this product excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness marked drowsiness may occur use caution when driving a motor vehicle or operating machinery avoid alcoholic beverages

Stop Use & Ask a Doctor

Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

Keep Out of Reach of Children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Storage & Handling

Other information store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) use by expiration date on package

Questions

Questions or comments? 1-800-426-9391


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