Fluocinonide FLUOCINONIDE ZYDUS PHARMACEUTICALS USA INC. FDA Approved Fluocinonide topical solution USP, 0.05% is intended for topical administration. The active component is the corticosteroid fluocinonide, which is the 21-acetate ester of fluocinolone acetonide and has the chemical name pregna-1,4 -diene-3,20 -dione,21-(acetyloxy)-6 ,9 -difluoro -11-hydro xy-16 ,17-[(1- methylethylidene)bis(oxy)]-,(6 α, 11β, 16 α)-. It has the following chemical structure: Fluocinonide, USP is white or almost white microcrystalline powder. It is practically insoluble in water, very slightly soluble in ether, slightly soluble in ethanol, methanol and dioxane, sparingly soluble in acetone and chloroform. Fluocinonide topical solution USP, 0.05% contains fluocinonide USP, 0.5 mg/mL in a solution of citric acid monohydrate, dehydrated alcohol (35%), diisopropyl adipate, propylene glycol and purified water. In this formulation, the active ingredient is totally in solution. Fluocinonide topical solution USP, 0.5%
FunFoxMeds bottle
Substance Fluocinonide
Route
TOPICAL
Applications
ANDA208948

Drug Facts

Composition & Profile

Strengths
0.05 % 20 ml 60 ml
Quantities
20 ml 60 ml
Treats Conditions
Indications And Usage Fluocinonide Topical Solution Usp 0 05 Is Indicated For The Relief Of The Inflammatory And Pruritic Manifestations Of Corticosteroid Responsive Dermatoses

Identifiers & Packaging

Container Type BOTTLE
UPC
0370710128432
UNII
2W4A77YPAN
Packaging

HOW SUPPLIED Fluocinonide Topical Solution USP, 0.05% is clear solution free from particulate matter and is supplied as: NDC 70710-1284-8 in bottle of 20 mL NDC 70710-1284-3 in bottle of 60 mL Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Avoid excessive heat, above 40°C (104°F). Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Please address medical inquiries to, ([email protected]) Tel.: 1-877-993-8779.; PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 70710-1284-3 Fluocinonide topical solution USP, 0.05% Rx only 60 mL Zydus Fluocinonide topical solution USP, 0.5% image Fluocinonide topical solution USP, 0.05%

Package Descriptions
  • HOW SUPPLIED Fluocinonide Topical Solution USP, 0.05% is clear solution free from particulate matter and is supplied as: NDC 70710-1284-8 in bottle of 20 mL NDC 70710-1284-3 in bottle of 60 mL Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Avoid excessive heat, above 40°C (104°F). Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Please address medical inquiries to, ([email protected]) Tel.: 1-877-993-8779.
  • PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 70710-1284-3 Fluocinonide topical solution USP, 0.05% Rx only 60 mL Zydus Fluocinonide topical solution USP, 0.5% image Fluocinonide topical solution USP, 0.05%

Overview

Fluocinonide topical solution USP, 0.05% is intended for topical administration. The active component is the corticosteroid fluocinonide, which is the 21-acetate ester of fluocinolone acetonide and has the chemical name pregna-1,4 -diene-3,20 -dione,21-(acetyloxy)-6 ,9 -difluoro -11-hydro xy-16 ,17-[(1- methylethylidene)bis(oxy)]-,(6 α, 11β, 16 α)-. It has the following chemical structure: Fluocinonide, USP is white or almost white microcrystalline powder. It is practically insoluble in water, very slightly soluble in ether, slightly soluble in ethanol, methanol and dioxane, sparingly soluble in acetone and chloroform. Fluocinonide topical solution USP, 0.05% contains fluocinonide USP, 0.5 mg/mL in a solution of citric acid monohydrate, dehydrated alcohol (35%), diisopropyl adipate, propylene glycol and purified water. In this formulation, the active ingredient is totally in solution. Fluocinonide topical solution USP, 0.5%

Indications & Usage

Fluocinonide topical solution USP, 0.05% is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Dosage & Administration

Fluocinonide topical solution USP, 0.05% is generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.

Warnings & Precautions
No warnings available yet.
Contraindications

Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Adverse Reactions

The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Hypertrichosis Maceration of the skin Itching Acneiform eruptions Secondary infection Irritation Hypopigmentation Skin atrophy Dryness Perioral dermatitis Striae Folliculitis Allergic contact dermatitis Miliaria


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