Severe Congestion and Cough, Cold and Flu Nighttime ACETAMINOPHEN DEXTROMETHORPHAN HBR GUAIFENESIN PHENYLEPHRINE HCL TRIPROLIDINE HCL WALGREEN COMPANY FDA Approved Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the intensity of coughing the impulse to cough to help you get to sleep nasal congestion due to a cold Uses temporarily relieves these common cold and flu symptoms: runny nose headache cough sneezing sore throat minor aches and pains itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep

Drug Facts

Composition & Profile

Active Ingredients
Active ingredients (in each 20 mL) Dextromethorphan HBr 20 mg Guaifenesin 400 mg Phenylephrine HCl 10 mg Active ingredients (in each 20 mL) Acetaminophen 650 mg Dextromethorphan HBr 20 mg Triprolidine HCl 2.5 mg
Inactive Ingredients
Inactive ingredients anhydrous citric acid FD&C blue #1 FD&C red #40 flavors glycerin propylene glycol purified water sodium benzoate sodium citrate dihydrate sodium metabisulfite sorbitol sucralose xanthan gum Inactive ingredients anhydrous citric acid FD&C blue #1 FD&C red #40 FD&C yellow #6 flavors glycerin propylene glycol purified water sodium benzoate sucralose xanthan gum
Strengths
20 ml 20 mg 400 mg 10 mg 650 mg 2.5 mg
Quantities
177 ml 355 ml
Treats Conditions
Uses Helps Loosen Phlegm Mucus And Thin Bronchial Secretions To Rid The Bronchial Passageways Of Bothersome Mucus And Make Coughs More Productive Temporarily Relieves Cough Due To Minor Throat And Bronchial Irritation As May Occur With The Common Cold Or Inhaled Irritants The Intensity Of Coughing The Impulse To Cough To Help You Get To Sleep Nasal Congestion Due To A Cold Uses Temporarily Relieves These Common Cold And Flu Symptoms Runny Nose Headache Cough Sneezing Sore Throat Minor Aches And Pains Itching Of The Nose Or Throat Itchy Watery Eyes Due To Hay Fever Temporarily Reduces Fever Controls Cough To Help You Get To Sleep
Pill Appearance
Color: blue

Identifiers & Packaging

Container Type BOTTLE
Packaging

Principal Display Panel NDC 0363-4063-45 DAY & NIGHT PACK Walgreens • WALGREENS • PHARMACIST RECOMMENDED † Compare to the active ingredients in MAXIMUM STRENGTH MUCINEX FAST-MAX® Severe Congestion & Cough & NIGHTSHIFT® Cold & Flu †† Severe Congestion & Cough DEXTROMETHORPHAN HBr / COUGH SUPPRESSANT GUAIFENESIN / EXPECTORANT PHENYLEPHRINE HCl / NASAL DECONGESTANT Maximum Strength • Controls cough • Relieves nasal & chest congestion • Thins & loosens mucus • 12 years & older NIGHTTIME Cold & Flu ACETAMINOPHEN / PAIN RELIEVER / FEVER REDUCER DEXTROMETHORPHAN HBr / COUGH SUPPRESSANT TRIPROLIDINE HCl / ANTIHISTAMINE Multi-Symptom • Relieves cough, fever, sore throat, runny nose & sneezing • 12 years & older 2 – 6 FL OZ (177 mL) BOTTLES / TOTAL 12 FL OZ (355 mL) TAMPER EVIDENT: DO NOT USE IF IMPRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING PARENTS: Learn about teen medicine abuse www.StopMedicineAbuse.org Do not take Severe Congestion & Cough and Nighttime Cold & Flu at the same time. 50844 REV0724A00406345 † Our pharmacists recommend the Walgreens brand. We invite you to compare to national brands. †† This product is not manufactured or distributed by RB Health (US) LLC, owner of the registered trademarks MAXIMUM STRENGTH MUCINEX FAST-MAX® and NIGHTSHIFT®. DISTRIBUTED BY: WALGREEN CO. DEERFIELD, IL 60015 100% SATISFACTION GUARANTEED walgreens.com ©2025 Walgreen Co. Walgreens 44-004063 Walgreens 44-004063

Package Descriptions
  • Principal Display Panel NDC 0363-4063-45 DAY & NIGHT PACK Walgreens • WALGREENS • PHARMACIST RECOMMENDED † Compare to the active ingredients in MAXIMUM STRENGTH MUCINEX FAST-MAX® Severe Congestion & Cough & NIGHTSHIFT® Cold & Flu †† Severe Congestion & Cough DEXTROMETHORPHAN HBr / COUGH SUPPRESSANT GUAIFENESIN / EXPECTORANT PHENYLEPHRINE HCl / NASAL DECONGESTANT Maximum Strength • Controls cough • Relieves nasal & chest congestion • Thins & loosens mucus • 12 years & older NIGHTTIME Cold & Flu ACETAMINOPHEN / PAIN RELIEVER / FEVER REDUCER DEXTROMETHORPHAN HBr / COUGH SUPPRESSANT TRIPROLIDINE HCl / ANTIHISTAMINE Multi-Symptom • Relieves cough, fever, sore throat, runny nose & sneezing • 12 years & older 2 – 6 FL OZ (177 mL) BOTTLES / TOTAL 12 FL OZ (355 mL) TAMPER EVIDENT: DO NOT USE IF IMPRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING PARENTS: Learn about teen medicine abuse www.StopMedicineAbuse.org Do not take Severe Congestion & Cough and Nighttime Cold & Flu at the same time. 50844 REV0724A00406345 † Our pharmacists recommend the Walgreens brand. We invite you to compare to national brands. †† This product is not manufactured or distributed by RB Health (US) LLC, owner of the registered trademarks MAXIMUM STRENGTH MUCINEX FAST-MAX® and NIGHTSHIFT®. DISTRIBUTED BY: WALGREEN CO. DEERFIELD, IL 60015 100% SATISFACTION GUARANTEED walgreens.com ©2025 Walgreen Co. Walgreens 44-004063 Walgreens 44-004063

Overview

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the intensity of coughing the impulse to cough to help you get to sleep nasal congestion due to a cold Uses temporarily relieves these common cold and flu symptoms: runny nose headache cough sneezing sore throat minor aches and pains itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep

Indications & Usage

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the intensity of coughing the impulse to cough to help you get to sleep nasal congestion due to a cold Uses temporarily relieves these common cold and flu symptoms: runny nose headache cough sneezing sore throat minor aches and pains itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep

Dosage & Administration

Directions do not take more than directed do not take more than 6 doses in any 24-hour period mL = milliliter only use the dose cup provided adults and children 12 years and over: 20 mL in dosing cup provided every 4 hours children under 12 years: do not use Directions do not take more than directed do not take more than 4 doses in any 24-hour period mL = milliliter only use the dose cup provided adults and children 12 years and over: 20 mL in dosing cup provided every 4 hours children under 12 years: do not use

Warnings & Precautions
Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have difficulty in urination due to enlargement of the prostate gland thyroid disease persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema high blood pressure heart disease diabetes cough that occurs with too much phlegm (mucus) When using this product do not exceed recommended dosage. Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur symptoms do not get better within 7 days or occur with fever cough persists more than 1 week, tends to recur, or is accompanied by a fever, rash, or persistent headache. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: rash blisters skin reddening If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have cough that occurs with too much phlegm (mucus) difficulty in urination due to enlargement of the prostate gland persistent or chronic cough such as occurs with smoking, asthma, or emphysema liver disease glaucoma a breathing problem such as emphysema or chronic bronchitis Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin When using this product excitability may occur, especially in children marked drowsiness may occur avoid alcoholic beverages alcohol, sedatives, and tranquilizers may increase drowsiness use caution when driving a motor vehicle or operating machinery Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Purpose

Purpose Cough suppressant Expectorant Nasal decongestant Purpose Pain reliever/fever reducer Cough suppressant Antihistamine

Do Not Use

Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

When Using

When using this product do not exceed recommended dosage. When using this product excitability may occur, especially in children marked drowsiness may occur avoid alcoholic beverages alcohol, sedatives, and tranquilizers may increase drowsiness use caution when driving a motor vehicle or operating machinery

Stop Use & Ask a Doctor

Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur symptoms do not get better within 7 days or occur with fever cough persists more than 1 week, tends to recur, or is accompanied by a fever, rash, or persistent headache. These could be signs of a serious condition. Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

Keep Out of Reach of Children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Storage & Handling

Other information each 20 mL contains: sodium 9 mg use by expiration date on package store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) Other information store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) use by expiration date on package

Questions

Questions or comments? 1-800-426-9391


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