Calcipotriene Cream, 0.005%, Calcipotriene Cream, 0.005% contains calcipotriene monohydrate, a synthetic vitamin D 3 derivative, for topical dermatological use. Chemically, calcipotriene monohydrate is (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol monohydrate, with the empirical formula C 27 H 40 O 3 •H 2 O, a molecular weight of 430.6, and the following structural formula: Calcipotriene monohydrate is a white or off-white crystalline substance. Calcipotriene Cream contains calcipotriene monohydrate equivalent to 50 μg/g anhydrous calcipotriene in a cream base of cetearyl alcohol, ceteth-20, diazolidinyl urea, dichlorobenzyl alcohol, dibasic sodium phosphate, edetate disodium, dl-alpha tocopherol, glycerin, mineral oil, petrolatum, and water. Structural formula for calcipotriene monohydrate

Calcipotriene Cream, 0.005%,

Mfr: OTC
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Drug Facts

Composition & Profile

Active Ingredients
ACTIVE INGREDIENT Dimethicone 5.0%
Inactive Ingredients
INACTIVE INGREDIENTS leurites Moluccana Seed Oil Aloe Barbadensis (Aloe Vera) Lead Juice SAFFLEXTM (Consisting of: Calcium Pantothenate (Vitamin B5) Maltodextrin Niacinamide (Vitamin B3) Pyridoxine HCl (Vitamin B6) Silica Sodium Ascorbyl Phosphate (Vitamin C) Sodium Starch Octenylsuccinate Tocopheryl Acetate (Vitamin E)) Bisabolol Butylene Glycol Caprylyl Glycol Carthamus Tinctorius (Safflower) Oleosomes Carthamus Tintorius (Safflower) Seed Oil Cetyl Alcohol Chlorphenesin Dimethicone Crosspolymer Disodium EDTA Glycerin Glyceryl Stearate Lavender Ylang Fragrance PEG-100 Stearate Pentaery Tetra-di-t-Butyl Hydroxyhydrocinnamate Phenoxyethanol Purified Water Sodium Hyaluronate Stearic Acid Triethanolamine Zingiber (Ginger) Root Extract.
Strengths
0.005 % 60 g 120 g 5.0 %
Treats Conditions
Indications And Usage Calcipotriene Cream 0 005 Is Indicated For The Treatment Of Plaque Psoriasis The Safety And Effectiveness Of Topical Calcipotriene In Dermatoses Other Than Psoriasis Have Not Been Established Uses For The Treatment And Or Prevention Of Diaper Rash Temporarily Protects And Helps Relieve Chapped Or Cracked Skin

Identifiers & Packaging

Container Type BOX
Packaging

HOW SUPPLIED Calcipotriene Cream, 0.005% is available in: 60 gram aluminum tubes (NDC 66993-877-61) 120 gram aluminum tubes (NDC 66993-877-78); DIMETHICONE THERA BODY SHIELD PDP; CALCIPOTRIENE CREAM 120G NDC 66993-877-78 Calcipotriene Cream 0.005% Net Wt. 120 g Rx only carton 120g; NuDermRxPAK 120 PDP

Package Descriptions
  • HOW SUPPLIED Calcipotriene Cream, 0.005% is available in: 60 gram aluminum tubes (NDC 66993-877-61) 120 gram aluminum tubes (NDC 66993-877-78)
  • DIMETHICONE THERA BODY SHIELD PDP
  • CALCIPOTRIENE CREAM 120G NDC 66993-877-78 Calcipotriene Cream 0.005% Net Wt. 120 g Rx only carton 120g
  • NuDermRxPAK 120 PDP

Overview

Calcipotriene Cream, 0.005% contains calcipotriene monohydrate, a synthetic vitamin D 3 derivative, for topical dermatological use. Chemically, calcipotriene monohydrate is (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol monohydrate, with the empirical formula C 27 H 40 O 3 •H 2 O, a molecular weight of 430.6, and the following structural formula: Calcipotriene monohydrate is a white or off-white crystalline substance. Calcipotriene Cream contains calcipotriene monohydrate equivalent to 50 μg/g anhydrous calcipotriene in a cream base of cetearyl alcohol, ceteth-20, diazolidinyl urea, dichlorobenzyl alcohol, dibasic sodium phosphate, edetate disodium, dl-alpha tocopherol, glycerin, mineral oil, petrolatum, and water. Structural formula for calcipotriene monohydrate

Indications & Usage

Calcipotriene Cream, 0.005%, is indicated for the treatment of plaque psoriasis. The safety and effectiveness of topical calcipotriene in dermatoses other than psoriasis have not been established. USES For the treatment and/or prevention of diaper rash Temporarily protects and helps relieve chapped or cracked skin

Dosage & Administration

Apply a thin layer of Calcipotriene Cream to the affected skin twice daily and rub in gently and completely. The safety and efficacy of Calcipotriene Cream have been demonstrated in patients treated for eight weeks.

Warnings & Precautions
WARNINGS Contact dermatitis, including allergic contact dermatitis, has been observed with the use of Calcipotriene Cream. WARNINGS For external use only
Contraindications

Calcipotriene Cream is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation. It should not be used by patients with demonstrated hypercalcemia or evidence of vitamin D toxicity. Calcipotriene Cream should not be used on the face.

Purpose

PURPOSE Skin Protectant

Do Not Use

DO NOT USE -deep or puncture wounds -animal bites -serious burns

When Using

WHEN USING THIS PRODUCT do not get into eyes

Stop Use & Ask a Doctor

STOP USE AND ASK A DOCTOR IF -condition worsens -symptoms last more than 7 days or clear up and occur again within a few days

Keep Out of Reach of Children

KEEP OUT OF REACH OF CHILDREN f swallowed, get medical help or contact a Poison Control Center right away.

Storage & Handling

STORAGE Store at controlled room temperature 15°C - 25°C (59°F - 77°F). Do not freeze. OTHER INFORMATION -Protect from freezing. Avoid excessive heat.


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