Hydrocortisone HYDROCORTISONE E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC. FDA Approved The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents. Hydrocortisone Cream USP, 2.5% and Hydrocortisone Ointment USP, 2.5% contains hydrocortisone, USP. Hydrocortisone is a white to practically white crystalline powder. Chemically, hydrocortisone is pregn-4-ene-3,20-dione, 11,17, 21-trihydroxy-, (11β)-. The structural formula of hydrocortisone is: Molecular Formula: C 21 H 30 O 5 Molecular Weight: 362.47 Each gram of the 2.5% Cream contains 25 mg of hydrocortisone, USP in a base of glyceryl monostearate, polyoxyl 40 stearate, glycerin, paraffin, stearyl alcohol, isopropyl palmitate, sorbitan monostearate, benzyl alcohol, potassium sorbate, lactic acid and purified water. Each gram of the 2.5% Ointment contains 25 mg of hydrocortisone, USP in a base of white petrolatum and mineral oil. chemical-structure
FunFoxMeds bottle
Substance Hydrocortisone
Route
TOPICAL
Applications
ANDA089414 ANDA081203

Drug Facts

Composition & Profile

Strengths
2.5 % 30 g 28.35 g 453.6 g
Quantities
31 count
Treats Conditions
Indications And Usage Topical Corticosteroids Are Indicated For The Relief Of The Inflammatory And Pruritic Manifestations Of Corticosteroid Responsive Dermatoses

Identifiers & Packaging

Container Type BOTTLE
UPC
0301680146300 0301680080314
UNII
WI4X0X7BPJ
Packaging

HOW SUPPLIED Hydrocortisone Cream USP, 2.5% Hydrocortisone Ointment USP, 2.5% a white cream is available as follows: a white ointment is available as follows: NDC 0168-0080-31 30 g Tubes NDC 0168-0146-30 28.35 g (1 oz) Tubes NDC 0168-0080-16 453.6 g (1 Lb) Jars NDC 0168-0146-16 453.6 g (1 Lb) Jars Store at controlled room temperature 15° to 30°C (59° to 86°F). E. FOUGERA & CO. A division of Fougera PHARMACEUTICALS INC. Melville, New York 11747 Rev. 07/2024; PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 1 OZ CONTAINER NDC 0168-0146-30 Hydrocortisone Ointment USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Rx only Each gram for topical administration contains: 25 mg of hydrocortisone, USP in a base of white petrolatum and mineral oil. Net Wt. 28.35 g (1 Oz) tube-ont; PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 1 OZ CARTON NDC 0168-0146-30 Rx only Hydrocortisone Ointment USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Net Wt. 28.35 g (1 Oz) carton-ont; PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 30 GM CONTAINER NDC 0168-0080-31 Hydrocortisone Cream USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Rx only Each gram for topical administration contains: 25 mg of hydrocortisone, USP in a base of glyceryl monostearate, polyoxyl 40 stearate, glycerin, paraffin, stearyl alcohol, isopropyl palmitate, sorbitan monostearate, benzyl alcohol, potassium sorbate, lactic acid and purified water. Net Wt. 30 grams tube-crm; PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 30 GM CARTON NDC 0168-0080-31 Rx only Hydrocortisone Cream USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Net Wt. 30 grams carton-crm

Package Descriptions
  • HOW SUPPLIED Hydrocortisone Cream USP, 2.5% Hydrocortisone Ointment USP, 2.5% a white cream is available as follows: a white ointment is available as follows: NDC 0168-0080-31 30 g Tubes NDC 0168-0146-30 28.35 g (1 oz) Tubes NDC 0168-0080-16 453.6 g (1 Lb) Jars NDC 0168-0146-16 453.6 g (1 Lb) Jars Store at controlled room temperature 15° to 30°C (59° to 86°F). E. FOUGERA & CO. A division of Fougera PHARMACEUTICALS INC. Melville, New York 11747 Rev. 07/2024
  • PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 1 OZ CONTAINER NDC 0168-0146-30 Hydrocortisone Ointment USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Rx only Each gram for topical administration contains: 25 mg of hydrocortisone, USP in a base of white petrolatum and mineral oil. Net Wt. 28.35 g (1 Oz) tube-ont
  • PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 1 OZ CARTON NDC 0168-0146-30 Rx only Hydrocortisone Ointment USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Net Wt. 28.35 g (1 Oz) carton-ont
  • PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 30 GM CONTAINER NDC 0168-0080-31 Hydrocortisone Cream USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Rx only Each gram for topical administration contains: 25 mg of hydrocortisone, USP in a base of glyceryl monostearate, polyoxyl 40 stearate, glycerin, paraffin, stearyl alcohol, isopropyl palmitate, sorbitan monostearate, benzyl alcohol, potassium sorbate, lactic acid and purified water. Net Wt. 30 grams tube-crm
  • PACKAGE LABEL – PRINCIPAL DISPLAY PANEL – 30 GM CARTON NDC 0168-0080-31 Rx only Hydrocortisone Cream USP, 2.5% For External Use Only Not for Ophthalmic Use FOUGERA ® Net Wt. 30 grams carton-crm

Overview

The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents. Hydrocortisone Cream USP, 2.5% and Hydrocortisone Ointment USP, 2.5% contains hydrocortisone, USP. Hydrocortisone is a white to practically white crystalline powder. Chemically, hydrocortisone is pregn-4-ene-3,20-dione, 11,17, 21-trihydroxy-, (11β)-. The structural formula of hydrocortisone is: Molecular Formula: C 21 H 30 O 5 Molecular Weight: 362.47 Each gram of the 2.5% Cream contains 25 mg of hydrocortisone, USP in a base of glyceryl monostearate, polyoxyl 40 stearate, glycerin, paraffin, stearyl alcohol, isopropyl palmitate, sorbitan monostearate, benzyl alcohol, potassium sorbate, lactic acid and purified water. Each gram of the 2.5% Ointment contains 25 mg of hydrocortisone, USP in a base of white petrolatum and mineral oil. chemical-structure

Indications & Usage

Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Dosage & Administration

Apply to the affected area as a thin film 2 to 4 times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.

Warnings & Precautions
No warnings available yet.
Contraindications

Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Adverse Reactions

The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria.


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