Mydriacyl TROPICAMIDE ALCON LABORATORIES, INC. FDA Approved MYDRIACYL™ (tropicamide ophthalmic solution, USP) is an anticholinergic prepared as a sterile topical ophthalmic solution in two strengths. The active ingredient is represented by the chemical structure: Each mL of MYDRIACYL™ (tropicamide ophthalmic solution, USP) contains: Active: tropicamide 1%. Preservative: benzalkonium chloride 0.01%. Inactives: sodium chloride, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water. pH range 4.0 - 5.8. chemical
FunFoxMeds bottle
Substance Tropicamide
Route
OPHTHALMIC
Applications
ANDA084306
Package NDC

Drug Facts

Composition & Profile

Strengths
3 ml 15 ml 1 %
Quantities
3 ml 15 ml
Treats Conditions
Indications And Usage For Mydriasis And Cycloplegia For Diagnostic Procedures

Identifiers & Packaging

Container Type BOTTLE
All Product Codes
UNII
N0A3Z5XTC6
Packaging

HOW SUPPLIED 3 mL and 15 mL in plastic DROP-TAINER ® dispensers. 1% 3 mL: NDC 0065-0355-03 15 mL: NDC 0998-0355-15 STORAGE: Store at 8° to 27°C (46° to 80°F). Do not refrigerate or store at high temperatures. Keep container tightly closed.; PRINCIPAL DISPLAY PANEL NDC 0998-0355-15 Alcon ® Mydriacyl ® 1% (tropicamide ophthalmic solution, USP) 15 mL Sterile Rx Only A Sterile Anticholinergic Agent. USUAL DOSAGE: One or two drops topically in the eye(s). Read enclosed insert. PRECAUTION: Do not touch dropper tip to any surface, as this may contaminate the solution. INGREDIENTS: Each mL Contains: Active: tropicamide 1%. Preservative: benzalkonium chloride 0.01%. Inactives: sodium chloride, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water. pH range 4.0-5.8. ©2002, 2010 Alcon, Inc. Alcon ® ALCON LABORATORIES, INC. Fort Worth, Texas. 76134 USA Product of Japan 9016373 US STORAGE: Store at 8º-27ºC (46º-80ºF). Do not refrigerate or store at high temperatures. Keep container tightly closed. FOR TOPICAL OPHTHALMIC USE ONLY. SN: LOT: EXP.: GTIN: 00309980355156 NDC 0998-0355-15 Alcon ® Mydriacyl ® 1% (tropicamide ophthalmic solution, USP) Sterile 15 mL Rx Only FOR TOPICAL OPHTHALMIC USE ONLY A Sterile Anticholinergic Agent. INGREDIENTS: Each mL Contains: Active: tropicamide 1%. Preservative: benzalkonium chloride 0.01%. Inactives: sodium chloride, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water. pH range 4.0-5.8. USUAL DOSAGE: One or two drops topically in the eye(s). Read enclosed insert. PRECAUTION: Do not touch dropper tip to any surface, as this may contaminate the solution. STORAGE: Store at 8º-27ºC (46º-80ºF). Do not refrigerate or store at high temperatures. Keep container tightly closed. ALCON LABORATORIES, INC. Fort Worth, Texas. 76134 USA Printed in USA ©2002, 2004 Alcon Laboratories, Inc. H15341 US LOT: EXP.:

Package Descriptions
  • HOW SUPPLIED 3 mL and 15 mL in plastic DROP-TAINER ® dispensers. 1% 3 mL: NDC 0065-0355-03 15 mL: NDC 0998-0355-15 STORAGE: Store at 8° to 27°C (46° to 80°F). Do not refrigerate or store at high temperatures. Keep container tightly closed.
  • PRINCIPAL DISPLAY PANEL NDC 0998-0355-15 Alcon ® Mydriacyl ® 1% (tropicamide ophthalmic solution, USP) 15 mL Sterile Rx Only A Sterile Anticholinergic Agent. USUAL DOSAGE: One or two drops topically in the eye(s). Read enclosed insert. PRECAUTION: Do not touch dropper tip to any surface, as this may contaminate the solution. INGREDIENTS: Each mL Contains: Active: tropicamide 1%. Preservative: benzalkonium chloride 0.01%. Inactives: sodium chloride, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water. pH range 4.0-5.8. ©2002, 2010 Alcon, Inc. Alcon ® ALCON LABORATORIES, INC. Fort Worth, Texas. 76134 USA Product of Japan 9016373 US STORAGE: Store at 8º-27ºC (46º-80ºF). Do not refrigerate or store at high temperatures. Keep container tightly closed. FOR TOPICAL OPHTHALMIC USE ONLY. SN: LOT: EXP.: GTIN: 00309980355156 NDC 0998-0355-15 Alcon ® Mydriacyl ® 1% (tropicamide ophthalmic solution, USP) Sterile 15 mL Rx Only FOR TOPICAL OPHTHALMIC USE ONLY A Sterile Anticholinergic Agent. INGREDIENTS: Each mL Contains: Active: tropicamide 1%. Preservative: benzalkonium chloride 0.01%. Inactives: sodium chloride, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water. pH range 4.0-5.8. USUAL DOSAGE: One or two drops topically in the eye(s). Read enclosed insert. PRECAUTION: Do not touch dropper tip to any surface, as this may contaminate the solution. STORAGE: Store at 8º-27ºC (46º-80ºF). Do not refrigerate or store at high temperatures. Keep container tightly closed. ALCON LABORATORIES, INC. Fort Worth, Texas. 76134 USA Printed in USA ©2002, 2004 Alcon Laboratories, Inc. H15341 US LOT: EXP.:

Overview

MYDRIACYL™ (tropicamide ophthalmic solution, USP) is an anticholinergic prepared as a sterile topical ophthalmic solution in two strengths. The active ingredient is represented by the chemical structure: Each mL of MYDRIACYL™ (tropicamide ophthalmic solution, USP) contains: Active: tropicamide 1%. Preservative: benzalkonium chloride 0.01%. Inactives: sodium chloride, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH), purified water. pH range 4.0 - 5.8. chemical

Indications & Usage

For mydriasis and cycloplegia for diagnostic procedures.

Dosage & Administration

For refraction, instill one or two drops of 1% solution in the eye(s), repeated in five minutes. If patient is not seen within 20 to 30 minutes, an additional drop may be instilled to prolong mydriatic effect. For examination of fundus, instill one or two drops of 0.5% solution 15 or 20 minutes prior to examination. Individuals with heavily pigmented irides may require higher strength or more doses. Mydriasis will reverse spontaneously with time, typically in 4 to 8 hours. However, in some cases, complete recovery may take up to 24 hours.

Warnings & Precautions
WARNINGS FOR TOPICAL OPHTHALMIC USE ONLY. NOT FOR INJECTION. This preparation may cause CNS disturbances which may be dangerous in pediatric patients. The possibility of psychotic reactions and behavioral disturbances due to hypersensitivity to anticholinergic drugs should be considered. Mydriatics may produce a transient elevation of intraocular pressure. Remove contact lenses before using.
Contraindications

Contraindicated in persons showing hypersensitivity to any component of this preparation.

Adverse Reactions

Ocular: Transient stinging, blurred vision, photophobia and superficial punctuate keratitis have been reported with the use of tropicamide. Increased intraocular pressure has been reported following the use of mydriatics. Non-Ocular: Dryness of the mouth, tachycardia, headache, allergic reactions, nausea, vomiting, pallor, central nervous system disturbances and muscle rigidity have been reported with the use of tropicamide. Psychotic reactions, behavioral disturbances, and vasomotor or cardiorespiratory collapse in children have been reported with the use of anticholinergic drugs.

Drug Interactions

Tropicamide may interfere with the antihypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.


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