Dextrose And Sodium Chloride DEXTROSE AND SODIUM CHLORIDE B. BRAUN MEDICAL INC. FDA Approved (See chart below for quantitative information.) Dextrose and Sodium Chloride Injections USP are sterile, nonpyrogenic and contain no bacteriostatic or antimicrobial agents. These products are intended for intravenous administration. The formulas of the active ingredients are: Ingredients Molecular Formula Molecular Weight Sodium Chloride USP NaCl 58.44 Hydrous Dextrose USP 198.17 Composition – Each 100 mL contains: Concentration of Electrolytes (mEq/liter) Hydrous Dextrose USP Sodium Chloride USP Calories per liter Calculated Osmolarity mOsmol/liter pH Solution Sodium Chloride Water for Injection USP qs 3.3% Dextrose and 0.30% Sodium Chloride Injection USP 3.3 g 0.3 g 51 51 110 270 4.5 (3.5–6.5) 5% Dextrose and 0.9% Sodium Chloride Injection USP 5 g 0.9 g 154 154 170 560 4.4 (3.5–6.5) 5% Dextrose and 0.45% Sodium Chloride Injection USP 5 g 0.45 g 77 77 170 405 4.4 (3.5–6.5) 5% Dextrose and 0.33% Sodium Chloride Injection USP 5 g 0.33 g 56 56 170 365 4.4 (3.5–6.5) 5% Dextrose and 0.20% Sodium Chloride Injection USP 5 g 0.2 g 34 34 170 320 4.4 (3.5–6.5) 10% Dextrose and 0.45% Sodium Chloride Injection USP 10 g 0.45 g 77 77 340 660 4.3 (3.5–6.5) 10% Dextrose and 0.20% Sodium Chloride Injection USP 10 g 0.2 g 34 34 340 575 4.3 (3.5–6.5) Not made with natural rubber latex, PVC or DEHP. The plastic container is made from a multilayered film specifically developed for parenteral drugs. It contains no plasticizers and exhibits virtually no leachables. The solution contact layer is a rubberized copolymer of ethylene and propylene. The container is nontoxic and biologically inert. The container-solution unit is a closed system and is not dependent upon entry of external air during administration. The container is overwrapped to provide protection from the physical environment and to provide an additional moisture barrier when necessary. Addition of medication should be accomplished using complete aseptic technique. The closure system has two ports; the one for the administration set has a tamper evident plastic protector and the other is a medication addition site. Refer to the Directions for Use of the container. Chemical Structure

Drug Facts

Composition & Profile

Strengths
1000 ml 500 ml 250 ml 3.3 % 0.30 % 5 % 0.9 % 0.45 % 0.33 % 0.20 % 10 %
Quantities
1000 ml 500 ml 250 ml 100 ml
Treats Conditions
Indications And Usage These Intravenous Solutions Are Indicated For Use In Adults And Pediatric Patients As Sources Of Electrolytes Calories And Water For Hydration

Identifiers & Packaging

Container Type BOTTLE
UNII
IY9XDZ35W2 451W47IQ8X
Packaging

HOW SUPPLIED Dextrose and Sodium Chloride Injections USP are supplied sterile and nonpyrogenic in EXCEL ® Containers. The 1000 mL containers are packaged 12 per case; the 500 mL and 250 mL containers are packaged 24 per case. Canada DIN NDC REF Size 3.3% Dextrose and 0.30% Sodium Chloride Injection USP 01927981 0264-7608-00 L6080-00 1000 mL 0264-7608-10 L6081-00 500 mL 5% Dextrose and 0.9% Sodium Chloride Injection USP 01924435 0264-7610-00 L6100 1000 mL 0264-7610-10 L6101 500 mL 5% Dextrose and 0.45% Sodium Chloride Injection USP 01927531 0264-7612-00 L6120 1000 mL 0264-7612-10 L6121 500 mL 0264-7612-20 L6122 250 mL 5% Dextrose and 0.33% Sodium Chloride Injection USP 0264-7614-00 L6140 1000 mL 0264-7614-10 L6141 500 mL 5% Dextrose and 0.20% Sodium Chloride Injection USP 01927558 0264-7616-00 L6160 1000 mL 0264-7616-10 L6161 500 mL 0264-7616-20 L6162 250 mL 10% Dextrose and 0.45% Sodium Chloride Injection USP 0264-7622-00 L6220 1000 mL 10% Dextrose and 0.20% Sodium Chloride Injection USP 0264-7623-20 L6232 250 mL Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at room temperature (25°C); however, brief exposure up to 40°C does not adversely affect the product.; PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 3.3% Dextrose and 0.30% Sodium Chloride Injection USP REF L6080-00 NDC 0264-7608-00 DIN 01927981 1000 mL EXCEL® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 3.3 g; Sodium Chloride USP 0.3 g; Water for Injection USP qs pH: 4.5 (3.5-6.5); Calc. Osmolarity: 270 mOsmol/liter Electrolytes (mEq/liter): Na + 51; Cl – 51 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-252 LD-183-3 EXP LOT Other 1000 mL Container Label L6080-00; PRINCIPAL DISPLAY PANEL - 500 mL Container Label 3.3% Dextrose and 0.30% Sodium Chloride Injection USP REF L6081-00 NDC 0264-7608-10 DIN 01927981 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 3.3 g; Sodium Chloride USP 0.3 g; Water for Injection USP qs pH: 4.5 (3.5-6.5); Calc. Osmolarity: 270 mOsmol/liter Electrolytes (mEq/liter): Na + 51; Cl – 51 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-246 LD-184-3 EXP LOT L6081-00 Other L6081-00; PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.9% Sodium Chloride Injection USP REF L6100 NDC 0264-7610-00 DIN 01924435 HK 22608 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.9 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 560 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 154; Cl – 154 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-253 LD-177-3 EXP LOT OTHER 1000 mL Container Label L6100; PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.9% Sodium Chloride Injection USP REF L6101 NDC 0264-7610-10 DIN 01924435 HK 22608 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.9 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 560 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 154; Cl – 154 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-247 LD-176-3 EXP LOT L6101 Other L6101; PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.45% Sodium Chloride Injection USP REF L6120 NDC 0264-7612-00 DIN 01927531 HK 22607 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 405 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-254 LD-108-3 EXP LOT OTHER 1000 mL Container Label L6120; PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.45% Sodium Chloride Injection USP REF L6121 NDC 0264-7612-10 DIN 01927531 HK 22607 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 405 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-248 LD-113-3 EXP LOT L6121 OTHER L6121; PRINCIPAL DISPLAY PANEL - 250 mL Container Label 5% Dextrose and 0.45% Sodium Chloride Injection USP REF L6122 NDC 0264-7612-20 DIN 01927531 HK 22607 250 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 405 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-245 LD-114-3 EXP LOT L6122 Other L6122; PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.33% Sodium Chloride Injection USP REF L6140 NDC 0264-7614-00 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.33 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 365 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 56; Cl – 56 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-255 LD-115-3 EXP LOT OTHER 500 mL Container Label L6140; PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.33% Sodium Chloride Injection USP REF L6141 NDC 0264-7614-10 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.33 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 365 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 56; Cl – 56 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-249 LD-174-3 EXP LOT L6141 OTHER L6141; PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.20% Sodium Chloride Injection USP REF L6160 NDC 0264-7616-00 DIN 01927558 HK 22606 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 320 mOsmol/liter Electrolytes (mEq/liter): Na + 34 ; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-256 LD-172-3 EXP LOT OTHER 1000 mL Container Label L6160; PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.20% Sodium Chloride Injection USP REF L6161 NDC 0264-7616-10 DIN 01927558 HK 22606 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 320 mOsmol/liter Electrolytes (mEq/liter): Na + 34; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-250 LD-112-3 EXP LOT L6161 OTHER L6161; PRINCIPAL DISPLAY PANEL - 250 mL Container Label 5% Dextrose and 0.20% Sodium Chloride Injection USP REF L6162 NDC 0264-7616-20 DIN 01927558 HK 22606 250 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 320 mOsmol/liter Electrolytes (mEq/liter): Na + 34; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-258 LD-171-3 EXP LOT L6162 Other L6162; PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 10% Dextrose and 0.45% Sodium Chloride Injection USP REF L6220 NDC 0264-7622-00 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 10 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.3 (3.5-6.5); Calc. Osmolarity: 660 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-257 LD-170-3 EXP LOT OTHER 1000 mL Container Label L6220; PRINCIPAL DISPLAY PANEL - 250 mL Container Label 10% Dextrose and 0.20% Sodium Chloride Injection USP REF L6232 NDC 0264-7623-20 250 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 10 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.3 (3.5-6.5); Calc. Osmolarity: 575 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 34; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-259 LD-169-4 EXP LOT L6232 OTHER L6232

Package Descriptions
  • HOW SUPPLIED Dextrose and Sodium Chloride Injections USP are supplied sterile and nonpyrogenic in EXCEL ® Containers. The 1000 mL containers are packaged 12 per case; the 500 mL and 250 mL containers are packaged 24 per case. Canada DIN NDC REF Size 3.3% Dextrose and 0.30% Sodium Chloride Injection USP 01927981 0264-7608-00 L6080-00 1000 mL 0264-7608-10 L6081-00 500 mL 5% Dextrose and 0.9% Sodium Chloride Injection USP 01924435 0264-7610-00 L6100 1000 mL 0264-7610-10 L6101 500 mL 5% Dextrose and 0.45% Sodium Chloride Injection USP 01927531 0264-7612-00 L6120 1000 mL 0264-7612-10 L6121 500 mL 0264-7612-20 L6122 250 mL 5% Dextrose and 0.33% Sodium Chloride Injection USP 0264-7614-00 L6140 1000 mL 0264-7614-10 L6141 500 mL 5% Dextrose and 0.20% Sodium Chloride Injection USP 01927558 0264-7616-00 L6160 1000 mL 0264-7616-10 L6161 500 mL 0264-7616-20 L6162 250 mL 10% Dextrose and 0.45% Sodium Chloride Injection USP 0264-7622-00 L6220 1000 mL 10% Dextrose and 0.20% Sodium Chloride Injection USP 0264-7623-20 L6232 250 mL Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at room temperature (25°C); however, brief exposure up to 40°C does not adversely affect the product.
  • PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 3.3% Dextrose and 0.30% Sodium Chloride Injection USP REF L6080-00 NDC 0264-7608-00 DIN 01927981 1000 mL EXCEL® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 3.3 g; Sodium Chloride USP 0.3 g; Water for Injection USP qs pH: 4.5 (3.5-6.5); Calc. Osmolarity: 270 mOsmol/liter Electrolytes (mEq/liter): Na + 51; Cl – 51 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-252 LD-183-3 EXP LOT Other 1000 mL Container Label L6080-00
  • PRINCIPAL DISPLAY PANEL - 500 mL Container Label 3.3% Dextrose and 0.30% Sodium Chloride Injection USP REF L6081-00 NDC 0264-7608-10 DIN 01927981 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 3.3 g; Sodium Chloride USP 0.3 g; Water for Injection USP qs pH: 4.5 (3.5-6.5); Calc. Osmolarity: 270 mOsmol/liter Electrolytes (mEq/liter): Na + 51; Cl – 51 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-246 LD-184-3 EXP LOT L6081-00 Other L6081-00
  • PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.9% Sodium Chloride Injection USP REF L6100 NDC 0264-7610-00 DIN 01924435 HK 22608 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.9 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 560 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 154; Cl – 154 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-253 LD-177-3 EXP LOT OTHER 1000 mL Container Label L6100
  • PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.9% Sodium Chloride Injection USP REF L6101 NDC 0264-7610-10 DIN 01924435 HK 22608 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.9 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 560 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 154; Cl – 154 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-247 LD-176-3 EXP LOT L6101 Other L6101
  • PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.45% Sodium Chloride Injection USP REF L6120 NDC 0264-7612-00 DIN 01927531 HK 22607 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 405 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-254 LD-108-3 EXP LOT OTHER 1000 mL Container Label L6120
  • PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.45% Sodium Chloride Injection USP REF L6121 NDC 0264-7612-10 DIN 01927531 HK 22607 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 405 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-248 LD-113-3 EXP LOT L6121 OTHER L6121
  • PRINCIPAL DISPLAY PANEL - 250 mL Container Label 5% Dextrose and 0.45% Sodium Chloride Injection USP REF L6122 NDC 0264-7612-20 DIN 01927531 HK 22607 250 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 405 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-245 LD-114-3 EXP LOT L6122 Other L6122
  • PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.33% Sodium Chloride Injection USP REF L6140 NDC 0264-7614-00 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.33 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 365 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 56; Cl – 56 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-255 LD-115-3 EXP LOT OTHER 500 mL Container Label L6140
  • PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.33% Sodium Chloride Injection USP REF L6141 NDC 0264-7614-10 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.33 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 365 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 56; Cl – 56 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-249 LD-174-3 EXP LOT L6141 OTHER L6141
  • PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 5% Dextrose and 0.20% Sodium Chloride Injection USP REF L6160 NDC 0264-7616-00 DIN 01927558 HK 22606 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 320 mOsmol/liter Electrolytes (mEq/liter): Na + 34 ; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-256 LD-172-3 EXP LOT OTHER 1000 mL Container Label L6160
  • PRINCIPAL DISPLAY PANEL - 500 mL Container Label 5% Dextrose and 0.20% Sodium Chloride Injection USP REF L6161 NDC 0264-7616-10 DIN 01927558 HK 22606 500 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 320 mOsmol/liter Electrolytes (mEq/liter): Na + 34; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-250 LD-112-3 EXP LOT L6161 OTHER L6161
  • PRINCIPAL DISPLAY PANEL - 250 mL Container Label 5% Dextrose and 0.20% Sodium Chloride Injection USP REF L6162 NDC 0264-7616-20 DIN 01927558 HK 22606 250 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 5 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.4 (3.5-6.5); Calc. Osmolarity: 320 mOsmol/liter Electrolytes (mEq/liter): Na + 34; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 In Canada, distributed by: B. Braun of Canada, Ltd. Scarborough, Ontario M1H 2W4 Y94-003-258 LD-171-3 EXP LOT L6162 Other L6162
  • PRINCIPAL DISPLAY PANEL - 1000 mL Container Label 10% Dextrose and 0.45% Sodium Chloride Injection USP REF L6220 NDC 0264-7622-00 1000 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 10 g; Sodium Chloride USP 0.45 g; Water for Injection USP qs pH: 4.3 (3.5-6.5); Calc. Osmolarity: 660 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 77; Cl – 77 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-257 LD-170-3 EXP LOT OTHER 1000 mL Container Label L6220
  • PRINCIPAL DISPLAY PANEL - 250 mL Container Label 10% Dextrose and 0.20% Sodium Chloride Injection USP REF L6232 NDC 0264-7623-20 250 mL EXCEL ® CONTAINER Each 100 mL contains: Hydrous Dextrose USP 10 g; Sodium Chloride USP 0.2 g; Water for Injection USP qs pH: 4.3 (3.5-6.5); Calc. Osmolarity: 575 mOsmol/liter, hypertonic Electrolytes (mEq/liter): Na + 34; Cl – 34 Sterile, nonpyrogenic. Single dose container. Do not use in series connection. For intravenous use only. Use only if solution is clear and container and seals are intact. WARNINGS: Do Not Administer Simultaneously With Blood. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Recommended Storage: Room temperature (25°C). Avoid excessive heat. Protect from freezing. See Package Insert. Do not remove overwrap until ready for use. After removing the overwrap, check for minute leaks by squeezing container firmly. If leaks are found, discard solution as sterility may be impaired. Not made with natural rubber latex, PVC or DEHP. Rx only EXCEL is a registered trademark of B. Braun Medical Inc. B. Braun Medical Inc. Bethlehem, PA 18018-3524 USA 1-800-227-2862 Y94-003-259 LD-169-4 EXP LOT L6232 OTHER L6232

Overview

(See chart below for quantitative information.) Dextrose and Sodium Chloride Injections USP are sterile, nonpyrogenic and contain no bacteriostatic or antimicrobial agents. These products are intended for intravenous administration. The formulas of the active ingredients are: Ingredients Molecular Formula Molecular Weight Sodium Chloride USP NaCl 58.44 Hydrous Dextrose USP 198.17 Composition – Each 100 mL contains: Concentration of Electrolytes (mEq/liter) Hydrous Dextrose USP Sodium Chloride USP Calories per liter Calculated Osmolarity mOsmol/liter pH Solution Sodium Chloride Water for Injection USP qs 3.3% Dextrose and 0.30% Sodium Chloride Injection USP 3.3 g 0.3 g 51 51 110 270 4.5 (3.5–6.5) 5% Dextrose and 0.9% Sodium Chloride Injection USP 5 g 0.9 g 154 154 170 560 4.4 (3.5–6.5) 5% Dextrose and 0.45% Sodium Chloride Injection USP 5 g 0.45 g 77 77 170 405 4.4 (3.5–6.5) 5% Dextrose and 0.33% Sodium Chloride Injection USP 5 g 0.33 g 56 56 170 365 4.4 (3.5–6.5) 5% Dextrose and 0.20% Sodium Chloride Injection USP 5 g 0.2 g 34 34 170 320 4.4 (3.5–6.5) 10% Dextrose and 0.45% Sodium Chloride Injection USP 10 g 0.45 g 77 77 340 660 4.3 (3.5–6.5) 10% Dextrose and 0.20% Sodium Chloride Injection USP 10 g 0.2 g 34 34 340 575 4.3 (3.5–6.5) Not made with natural rubber latex, PVC or DEHP. The plastic container is made from a multilayered film specifically developed for parenteral drugs. It contains no plasticizers and exhibits virtually no leachables. The solution contact layer is a rubberized copolymer of ethylene and propylene. The container is nontoxic and biologically inert. The container-solution unit is a closed system and is not dependent upon entry of external air during administration. The container is overwrapped to provide protection from the physical environment and to provide an additional moisture barrier when necessary. Addition of medication should be accomplished using complete aseptic technique. The closure system has two ports; the one for the administration set has a tamper evident plastic protector and the other is a medication addition site. Refer to the Directions for Use of the container. Chemical Structure

Indications & Usage

These intravenous solutions are indicated for use in adults and pediatric patients as sources of electrolytes, calories and water for hydration.

Dosage & Administration

These solutions are for intravenous use only. Dosage is to be directed by a physician and is dependent upon age, weight, clinical condition of the patient and laboratory determinations. Frequent laboratory determinations and clinical evaluation are essential to monitor changes in blood glucose and electrolyte concentrations, and fluid and electrolyte balance during prolonged parenteral therapy. When a hypertonic solution is to be administered peripherally, it should be slowly infused through a small bore needle, placed well within the lumen of a large vein to minimize venous irritation. Carefully avoid infiltration. In the average adult, daily requirements of sodium and chloride are met by the infusion of one liter of fluid containing 0.9% sodium chloride (154 mEq each of sodium and chloride). Fluid administration should be based on calculated maintenance or replacement fluid requirements for each patient. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Pediatric Use There is no specific pediatric dose. The dose is dependent on weight, clinical condition, and laboratory results. See WARNINGS and PRECAUTIONS .

Warnings & Precautions
WARNINGS The administration of intravenous solutions can cause fluid and/or solute overload resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentration. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentration. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states in which there is sodium retention with edema. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. Infusion of isotonic (0.9%) sodium chloride during or immediately after surgery may result in excessive sodium retention. Use the patient's circulatory system status as a guide. Excessive administration of potassium-free dextrose solutions may result in significant hypokalemia. Serum potassium levels should be maintained and potassium supplemented as required. Solutions containing dextrose and low electrolyte concentrations should not be administered simultaneously with blood through the same infusion set because of the possibility of pseudoagglutination or hemolysis.
Contraindications

These solutions are contraindicated where the administration of sodium or chloride could be clinically detrimental. Solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products.

Adverse Reactions

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. Too rapid infusion of hypertonic solutions may cause local pain and venous irritation. Rate of administration should be adjusted according to tolerance. Use of the largest peripheral vein and a small bore needle is recommended. (See DOSAGE AND ADMINISTRATION .) Symptoms may result from an excess or deficit of one or more of the ions present in the solution; therefore, frequent monitoring of electrolyte levels is essential. Hypernatremia may be associated with edema and exacerbation of congestive heart failure due to the retention of water, resulting in an expanded extracellular fluid volume. If infused in large amounts, chloride ions may cause a loss of bicarbonate ions, resulting in an acidifying effect. The physician should also be alert to the possibility of adverse reactions to drug additives diluted and administered from the plastic container. Prescribing information for drug additives to be administered in this manner should be consulted. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Storage & Handling

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at room temperature (25°C); however, brief exposure up to 40°C does not adversely affect the product.


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