Nystatin NYSTATIN AMERICAN HEALTH PACKAGING FDA Approved Nystatin is an antimycotic polyene antibiotic obtained from Streptomyces noursei . Structural formula: Nystatin Oral Suspension USP, for oral administration, contains 100,000 USP Nystatin Units per mL. Inactive ingredients: alcohol (≤ 1% v/v), artificial peppermint flavor, cherry flavor, citric acid, D&C Yellow No. 10, FD&C Red No. 40, glycerin, magnesium aluminum silicate, methylparaben, potassium phosphate dibasic, propylene glycol, propylparaben, purified water and sucrose. Structural Formula
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Substance Nystatin
Route
ORAL
Applications
ANDA203621

Drug Facts

Composition & Profile

Strengths
5 ml
Quantities
5 ml
Treats Conditions
Indications And Usage Nystatin Oral Suspension Is Indicated For The Treatment Of Candidiasis In The Oral Cavity
Pill Appearance
Color: yellow

Identifiers & Packaging

Container Type UNKNOWN
UNII
BDF1O1C72E
Packaging

HOW SUPPLIED Nystatin Oral Suspension USP, 100,000 USP Nystatin Units per mL, is available in a cherry, peppermint flavored, light creamy yellow, ready-to-use suspension, supplied in the following oral dosage form: 5 mL unit dose cups: 100 cups (10 x 10) NDC 60687-800-17 Storage: Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature]. Avoid freezing. DO NOT USE IF SEAL IS BROKEN.; Package/Label Display Panel - Cup Lid - 500,000 UNITS/5 ML Rx Only NDC 60687- 800 -40 NYSTATIN ORAL SUSPENSION, USP 500,000 units/5 mL Alcohol ≤1% v/v SHAKE WELL Delivers 5 mL Avoid freezing See package insert for full prescribing information and storage. For Institutional Use Only American Health Packaging Columbus, OH 43217 F0868C050124 500000 units per 5 mL Nystatin Oral Suspension Cup Lid

Package Descriptions
  • HOW SUPPLIED Nystatin Oral Suspension USP, 100,000 USP Nystatin Units per mL, is available in a cherry, peppermint flavored, light creamy yellow, ready-to-use suspension, supplied in the following oral dosage form: 5 mL unit dose cups: 100 cups (10 x 10) NDC 60687-800-17 Storage: Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature]. Avoid freezing. DO NOT USE IF SEAL IS BROKEN.
  • Package/Label Display Panel - Cup Lid - 500,000 UNITS/5 ML Rx Only NDC 60687- 800 -40 NYSTATIN ORAL SUSPENSION, USP 500,000 units/5 mL Alcohol ≤1% v/v SHAKE WELL Delivers 5 mL Avoid freezing See package insert for full prescribing information and storage. For Institutional Use Only American Health Packaging Columbus, OH 43217 F0868C050124 500000 units per 5 mL Nystatin Oral Suspension Cup Lid

Overview

Nystatin is an antimycotic polyene antibiotic obtained from Streptomyces noursei . Structural formula: Nystatin Oral Suspension USP, for oral administration, contains 100,000 USP Nystatin Units per mL. Inactive ingredients: alcohol (≤ 1% v/v), artificial peppermint flavor, cherry flavor, citric acid, D&C Yellow No. 10, FD&C Red No. 40, glycerin, magnesium aluminum silicate, methylparaben, potassium phosphate dibasic, propylene glycol, propylparaben, purified water and sucrose. Structural Formula

Indications & Usage

Nystatin Oral Suspension is indicated for the treatment of candidiasis in the oral cavity.

Dosage & Administration

INFANTS: 2 mL (200,000 units) four times daily (in infants and young children, use dropper to place one-half of dose in each side of mouth and avoid feeding for 5 to 10 minutes). NOTE: Limited clinical studies in premature and low birth weight infants indicate that 1 mL four times daily is effective. CHILDREN AND ADULTS: 4 to 6 mL (400,000 to 600,000 units) four times daily (one-half of dose in each side of mouth). The preparation should be retained in the mouth as long as possible before swallowing. Continue treatment for at least 48 hours after perioral symptoms have disappeared and cultures demonstrate eradication of Candida albicans .

Warnings & Precautions
No warnings available yet.
Contraindications

The preparation is contraindicated in patients with a history of hypersensitivity to any of its components.

Adverse Reactions

Nystatin is well tolerated even with prolonged therapy. Oral irritation and sensitization have been reported. (See PRECAUTIONS: General ). Gastrointestinal: Diarrhea (including one case of bloody diarrhea), nausea, vomiting, gastrointestinal upset/disturbances. Dermatologic: Rash, including urticaria has been reported rarely. Stevens-Johnson syndrome has been reported very rarely. Other: Tachycardia, bronchospasm, facial swelling, and non-specific myalgia have also been rarely reported. To report SUSPECTED ADVERSE REACTIONS, contact Pharmaceutical Associates, Inc. at 1-800-845-8210 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch .


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