Messer Pr - Nitrogen Nf Bulk Liquid -016

Messer Pr - Nitrogen Nf Bulk Liquid -016
SPL v16
SPL
SPL Set ID a64bb3c9-3947-d2f3-a219-24b58ec41abc
Route
RESPIRATORY (INHALATION)
Published
Effective Date 2025-11-18
Document Type 34391-3 HUMAN PRESCRIPTION DRUG LABEL

Drug Facts

Composition & Product

Active Ingredients
Nitrogen (995 mL)

Identifiers & Packaging

Marketing Status
NDA Active Since 1960-01-01

Description

Certificate of Analysis – Nitrogen, NF Customer                    Vendor / Supplier This letter is to provide you with the Certification you requested for Nitrogen, NF, Lot #. supplied to you in cylinders / vessels by our location. These cylinders were filled in accordance with the Standard Operating Procedures utilized for the manufacture of Medical Gases. By following these procedures, our location ensures that products are safely manufactured in compliance with FDA’s Current Good Manufacturing Practices (cGMP) Regulations and FDA Medical Gas Guidelines. CAUTION: Vendor supplies this certification to customer to assist customer in ensuring compliance with 21 CFR 211.84. This certification does not eliminate customer’s obligation to comply with other portions of 21 CFR 210 & 211 including but not limited to 21 CFR 211.265 (finished product testing) for cylinders and vessels filled from these supply cylinders. These cylinders are not certified for instrument calibration purposes. Test / Requirement NF Specification Lot Analysis Identification Pass Odor No appreciable odor Oxygen < 1.0 % Carbon Monoxide ≤10 ppm Assay ≥ 99.0 % The methodology being used to perform the NF Test for Assay is indicated below: Paramagnetic Analyzer   Model # Electrochemical Analyzer Model # These analyzers have been validated as acceptable alternatives to the official NF Gas Chromatography method for Nitrogen Assay. Validation study documentation is available. Gas Chromatography Official USP / NF method. Supplier Signature Date


Medication Information

Description

Certificate of Analysis – Nitrogen, NF Customer                    Vendor / Supplier This letter is to provide you with the Certification you requested for Nitrogen, NF, Lot #. supplied to you in cylinders / vessels by our location. These cylinders were filled in accordance with the Standard Operating Procedures utilized for the manufacture of Medical Gases. By following these procedures, our location ensures that products are safely manufactured in compliance with FDA’s Current Good Manufacturing Practices (cGMP) Regulations and FDA Medical Gas Guidelines. CAUTION: Vendor supplies this certification to customer to assist customer in ensuring compliance with 21 CFR 211.84. This certification does not eliminate customer’s obligation to comply with other portions of 21 CFR 210 & 211 including but not limited to 21 CFR 211.265 (finished product testing) for cylinders and vessels filled from these supply cylinders. These cylinders are not certified for instrument calibration purposes. Test / Requirement NF Specification Lot Analysis Identification Pass Odor No appreciable odor Oxygen < 1.0 % Carbon Monoxide ≤10 ppm Assay ≥ 99.0 % The methodology being used to perform the NF Test for Assay is indicated below: Paramagnetic Analyzer   Model # Electrochemical Analyzer Model # These analyzers have been validated as acceptable alternatives to the official NF Gas Chromatography method for Nitrogen Assay. Validation study documentation is available. Gas Chromatography Official USP / NF method. Supplier Signature Date

Section 51945-4

Certificate of Analysis – Nitrogen, NF

Customer                    Vendor / Supplier

This letter is to provide you with the Certification you requested for Nitrogen, NF, Lot #.

supplied to you in cylinders / vessels by our location.

These cylinders were filled in accordance with the Standard Operating Procedures utilized for the manufacture of

Medical Gases. By following these procedures, our location ensures that products are safely manufactured in

compliance with FDA’s Current Good Manufacturing Practices (cGMP) Regulations and FDA Medical Gas Guidelines.

CAUTION: Vendor supplies this certification to customer to assist customer in ensuring compliance with 21 CFR

211.84. This certification does not eliminate customer’s obligation to comply with other portions of 21 CFR 210 & 211

including but not limited to 21 CFR 211.265 (finished product testing) for cylinders and vessels filled from these supply

cylinders. These cylinders are not certified for instrument calibration purposes.

Test / Requirement

NF Specification

Lot Analysis

Identification

Pass

Odor

No appreciable odor

Oxygen

< 1.0 %

Carbon Monoxide

≤10 ppm

Assay

≥ 99.0 %

The methodology being used to perform the NF Test for Assay is indicated below:

Paramagnetic Analyzer   Model #

Electrochemical Analyzer Model #

These analyzers have been validated as acceptable alternatives to the official NF Gas Chromatography

method for Nitrogen Assay. Validation study documentation is available.

Gas Chromatography

Official USP / NF method.

Supplier Signature Date


Structured Label Content

Section 51945-4 (51945-4)

Certificate of Analysis – Nitrogen, NF

Customer                    Vendor / Supplier

This letter is to provide you with the Certification you requested for Nitrogen, NF, Lot #.

supplied to you in cylinders / vessels by our location.

These cylinders were filled in accordance with the Standard Operating Procedures utilized for the manufacture of

Medical Gases. By following these procedures, our location ensures that products are safely manufactured in

compliance with FDA’s Current Good Manufacturing Practices (cGMP) Regulations and FDA Medical Gas Guidelines.

CAUTION: Vendor supplies this certification to customer to assist customer in ensuring compliance with 21 CFR

211.84. This certification does not eliminate customer’s obligation to comply with other portions of 21 CFR 210 & 211

including but not limited to 21 CFR 211.265 (finished product testing) for cylinders and vessels filled from these supply

cylinders. These cylinders are not certified for instrument calibration purposes.

Test / Requirement

NF Specification

Lot Analysis

Identification

Pass

Odor

No appreciable odor

Oxygen

< 1.0 %

Carbon Monoxide

≤10 ppm

Assay

≥ 99.0 %

The methodology being used to perform the NF Test for Assay is indicated below:

Paramagnetic Analyzer   Model #

Electrochemical Analyzer Model #

These analyzers have been validated as acceptable alternatives to the official NF Gas Chromatography

method for Nitrogen Assay. Validation study documentation is available.

Gas Chromatography

Official USP / NF method.

Supplier Signature Date


Advanced Ingredient Data


Raw Label Data

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