SPL v3
SPL
SPL Set ID 47762f8f-30e2-445d-aaa1-e04479f8dd5b
Route
ORAL
Published
Effective Date 2022-03-23
Document Type 34390-5 HUMAN OTC DRUG LABEL

Drug Facts

Composition & Product

Active Ingredients
Iodide Ion (65 mg)
Inactive Ingredients
Lactose, Unspecified Form Microcrystalline Cellulose Magnesium Stearate

Identifiers & Packaging

Pill Appearance
Shape: round Color: white Size: 9 mm Score: 4
Marketing Status
ANDA Active Since 2002-09-30

Description

Take potassium iodide (KI) only when public officials tell you. In a nuclear radiation emergency, radioactive iodine could be released into the air. KI protects only the thyroid gland from uptake of radioactive iodine. Therefore, KI should be used along with other emergency measures that will be recommended to you by public officials. If you are told to take this medicine, take it 1 time every 24 hours. Do not take it more often. More KI will not help you. Too much KI may increase the chances of side effects. Do not take this medicine if you know you are allergic to iodine (see SIDE EFFECTS below).


Medication Information

Recent Major Changes

Take potassium iodide (KI) only when public officials tell you. In a nuclear radiation emergency, radioactive iodine could be released into the air. KI protects only the thyroid gland from uptake of radioactive iodine. Therefore, KI should be used along with other emergency measures that will be recommended to you by public officials. If you are told to take this medicine, take it 1 time every 24 hours. Do not take it more often. More KI will not help you. Too much KI may increase the chances of side effects. Do not take this medicine if you know you are allergic to iodine (see SIDE EFFECTSbelow).

Warnings and Precautions

WARNING

People who are allergic to iodine, have dermatitis herpetiformis or hypocomplementemic vasculitis, or have nodular thyroid disease with heart disease should not take KI. Keep out of the reach of children. In case of an allergic reaction (difficulty breathing, speaking or swallowing; wheezing; shortness of breath or swelling of the mouth or throat), call 911 or get medical care right away. In case of overdose, get medical help or call a Poison Control Center right away.

Indications and Usage

DIRECTIONS FOR USE

Use only as directed by public officials if a nuclear radiation emergency happens.

Dosage and Administration

Dose:

Adults over 18 years 2 tablets (whole or crushed) every day (130 mg)
Children over 12 years to 18 years who weigh at least 150 pounds 2 tablets (whole or crushed) every day (130 mg)
Children over 12 years to 18 years who weigh less than 150 pounds 1 tablet (whole or crushed) or 8 teaspoons every day (65 mg)
Children over 3 years to 12 years 1 tablet (whole or crushed) or 8 teaspoons every day (65 mg)
Children over 1 month to 3 years 4 teaspoons every day (32.5 mg)
Babies at birth to 1 month 2 teaspoons every day (16.25 mg)

Tablets can be crushed and mixed in many liquids. To take the tablet in liquid solution, use dosing directions under Making a Potassium Iodide Liquid Mixture.

Take KI every day (every 24 hours) as directed by public officials. Do not take more than 1 dose in 24 hours. More will not help you. Too much medicine may increase the chances of side effects.



Making a Potassium Iodide Liquid Mixture:

  • Put one65 mg KI tablet into a small bowl and grind it into a fine powder using the back of a metal teaspoon against the inside of the bowl. The powder should not have any large pieces.
  • Add 4 teaspoons of water to the crushed KI powder in the bowl and mix until the KI powder is dissolved in the water.
  • Take the KI water mixture solution made in step 2 and mix it with 4 teaspoons of low fat white or chocolate milk, orange juice, flat soda, raspberry syrup, or infant formula.
  • The KI liquid mixture will keep for up to 7 days in the refrigerator. It is recommended that the KI liquid mixtures be prepared weekly. Throw away unused portions.

The amount of KI (65 mg tablet) in the drink when mixed as described above is 8.125 mg per teaspoon. The number of teaspoons of the drink to give your child depends on your child’s age as described in the following table:

Child’s Age Give your child this amount in teaspoons
Over 12 to 18 years old who weigh less than 150 pounds 8 teaspoons will give you a 65 mg dose
Over 3 to 12 years old 8 teaspoons will give you a 65 mg dose
Over 1 month to 3 years old 4 teaspoons will give you a 32.5 mg dose
Birth to 1 month 2 teaspoons will give you a 16.25 mg dose

Note: This is the amount to give your child for onesingle dose in teaspoons (nottablespoons). You should give your child onedose each day as recommended by the public officials.

Pregnant or breastfeeding women or babies under 1 month of age:Take as directed above and call a doctor as soon as possible. Repeat dosing should be avoided. It is recommended that thyroid function be checked in babies less than 1 month of age that take KI. Women who are pregnant or breastfeeding should also be checked by a doctor if repeat dosing is necessary. Although these precautions should be taken, the benefits of short-term use of KI to block uptake of radioactive iodine by the thyroid gland far exceed its chances of side effects.

Patients with thyroid disease:If you have both a nodular thyroid condition such as multinodular goiter with heart disease, you should not take KI. Patients with other thyroid conditions may take KI as directed above, but call a doctor if you need to take KI for more than a few days.

Description

Take potassium iodide (KI) only when public officials tell you. In a nuclear radiation emergency, radioactive iodine could be released into the air. KI protects only the thyroid gland from uptake of radioactive iodine. Therefore, KI should be used along with other emergency measures that will be recommended to you by public officials. If you are told to take this medicine, take it 1 time every 24 hours. Do not take it more often. More KI will not help you. Too much KI may increase the chances of side effects. Do not take this medicine if you know you are allergic to iodine (see SIDE EFFECTS below).

Section 42229-5

HOW POTASSIUM IODIDE WORKS

Certain forms of iodine help your thyroid gland work right. Most people get the iodine they need from foods like iodized salt or fish. The thyroid can "store" or hold only a certain amount of iodine.

In a nuclear radiation emergency, radioactive iodine may be released in the air. This material may be breathed or swallowed. It may enter the thyroid gland and damage it. The damage would probably not show itself for years. Children are most likely to have thyroid damage.

If you take KI, it will block or reduce the chances that radioactive iodine will enter your thyroid gland.

Section 50565-1

Carton Label - Principal Display Panel

NDC-50633-910-20

ThyroSafe ®

Potassium Iodide Tablets, USP, 65 mg

Thyroid blocking in a radiation emergency only

20 tablets, 65 milligrams each

Carton Label – Back panel

Potassium Iodide (KI) Tablets USP, 65 mg

Drug Facts
Active Ingredient (in each tablet)

Potassium Iodide 65 mg
Purpose

Thyroid blocking
Usehelps prevent radioactive iodine from getting into the thyroid gland during a nuclear radiation emergency. Use along with other emergency measures recommended by public officials.
Warnings

Allergy alert:
Iodine may cause an allergic reaction with 1 or more of the following symptoms:
  • shortness of breath or wheezing
  • swelling
  • skin rash
  • trouble breathing, speaking or swallowing
  • fever and joint pain
Do not useif you have
  • ever had an allergic reaction to iodine
  • nodular thyroid disease with heart disease
  • hypocomplementemic vasculitis
  • dermatitis herpetiformis
Stop use and ask a doctor if you haveif you have
  • allergic reaction. Get medical help right away if you have trouble breathing, speaking or swallowing; shortness of breath; wheezing; swelling of the mouth, tongue or throat; or rash.
  • irregular heart or chest pain. Get medical help right away.
  • swelling of the hands or feet, fever, or joint pain.
Keep out of reach of children.In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
  • use as directed by public officials in the event of a nuclear radiation emergency.
  • do not take more than 1 dose in 24 hours.
  • tablets can be whole or crushed and mixed in milk, baby formula, water, orange juice, flat soda like cola, or raspberry syrup.

The liquid mixture should be given to infants, young children, and others who cannot swallow tablets; see consumer package insert on how to make a liquid mixture.

adults over 18 years 2 tablets (whole or crushed) daily (130 mg)
children over 12 years to 18 years who weigh at least 150 pounds 2 tablets (whole or crushed) daily (130 mg)
children over 12 years to 18 years who weigh less than 150 pounds 1 tablet (whole or crushed) daily (65 mg)
children over 3 years to 12 years 1 tablet (whole or crushed) daily (65 mg)
children over 1 month to 3 years 1/2 tablet (crushed) 32.5 mg daily as directed in the consumer package insert
babies at birth to 1 month 16.25 mg daily as directed in consumer package insert
If pregnant, breastfeeding, have a baby up to 1 month of age, or have thyroid disease(except nodular thyroid disease with heart disease), take as directed above and contact a doctor as soon as possible
Section 51727-6

Inactive ingredients

lactose, magnesium stearate, microcrystalline cellulose

Questions or comments?

call toll free 1-866-849-7672

Section 55105-1

INDICATIONS

ThyroSafe® (Potassium Iodide Tablets, USP) is a thyroid blocking medicine that is used in a nuclear radiation emergency only.

Section 55106-9

DESCRIPTION

Each white, round, cross-scored ThyroSafe® tablet contains 65 mg of potassium iodide.

Principal Display Panel Pack Label

Principal Display Panel 65 Mg Carton Label

NDC-50633-910-20

ThyroSafe ®

Potassium Iodide Tablets, USP, 65 mg

Thyroid blocking in a radiation emergency only

20 tablets, 65 milligrams each

BTG International Inc.


Structured Label Content

Recent Major Changes (34066-1)

Take potassium iodide (KI) only when public officials tell you. In a nuclear radiation emergency, radioactive iodine could be released into the air. KI protects only the thyroid gland from uptake of radioactive iodine. Therefore, KI should be used along with other emergency measures that will be recommended to you by public officials. If you are told to take this medicine, take it 1 time every 24 hours. Do not take it more often. More KI will not help you. Too much KI may increase the chances of side effects. Do not take this medicine if you know you are allergic to iodine (see SIDE EFFECTSbelow).

Indications and Usage (34067-9)

DIRECTIONS FOR USE

Use only as directed by public officials if a nuclear radiation emergency happens.

Dosage and Administration (34068-7)

Dose:

Adults over 18 years 2 tablets (whole or crushed) every day (130 mg)
Children over 12 years to 18 years who weigh at least 150 pounds 2 tablets (whole or crushed) every day (130 mg)
Children over 12 years to 18 years who weigh less than 150 pounds 1 tablet (whole or crushed) or 8 teaspoons every day (65 mg)
Children over 3 years to 12 years 1 tablet (whole or crushed) or 8 teaspoons every day (65 mg)
Children over 1 month to 3 years 4 teaspoons every day (32.5 mg)
Babies at birth to 1 month 2 teaspoons every day (16.25 mg)

Tablets can be crushed and mixed in many liquids. To take the tablet in liquid solution, use dosing directions under Making a Potassium Iodide Liquid Mixture.

Take KI every day (every 24 hours) as directed by public officials. Do not take more than 1 dose in 24 hours. More will not help you. Too much medicine may increase the chances of side effects.



Making a Potassium Iodide Liquid Mixture:

  • Put one65 mg KI tablet into a small bowl and grind it into a fine powder using the back of a metal teaspoon against the inside of the bowl. The powder should not have any large pieces.
  • Add 4 teaspoons of water to the crushed KI powder in the bowl and mix until the KI powder is dissolved in the water.
  • Take the KI water mixture solution made in step 2 and mix it with 4 teaspoons of low fat white or chocolate milk, orange juice, flat soda, raspberry syrup, or infant formula.
  • The KI liquid mixture will keep for up to 7 days in the refrigerator. It is recommended that the KI liquid mixtures be prepared weekly. Throw away unused portions.

The amount of KI (65 mg tablet) in the drink when mixed as described above is 8.125 mg per teaspoon. The number of teaspoons of the drink to give your child depends on your child’s age as described in the following table:

Child’s Age Give your child this amount in teaspoons
Over 12 to 18 years old who weigh less than 150 pounds 8 teaspoons will give you a 65 mg dose
Over 3 to 12 years old 8 teaspoons will give you a 65 mg dose
Over 1 month to 3 years old 4 teaspoons will give you a 32.5 mg dose
Birth to 1 month 2 teaspoons will give you a 16.25 mg dose

Note: This is the amount to give your child for onesingle dose in teaspoons (nottablespoons). You should give your child onedose each day as recommended by the public officials.

Pregnant or breastfeeding women or babies under 1 month of age:Take as directed above and call a doctor as soon as possible. Repeat dosing should be avoided. It is recommended that thyroid function be checked in babies less than 1 month of age that take KI. Women who are pregnant or breastfeeding should also be checked by a doctor if repeat dosing is necessary. Although these precautions should be taken, the benefits of short-term use of KI to block uptake of radioactive iodine by the thyroid gland far exceed its chances of side effects.

Patients with thyroid disease:If you have both a nodular thyroid condition such as multinodular goiter with heart disease, you should not take KI. Patients with other thyroid conditions may take KI as directed above, but call a doctor if you need to take KI for more than a few days.

Warnings and Precautions (34071-1)

WARNING

People who are allergic to iodine, have dermatitis herpetiformis or hypocomplementemic vasculitis, or have nodular thyroid disease with heart disease should not take KI. Keep out of the reach of children. In case of an allergic reaction (difficulty breathing, speaking or swallowing; wheezing; shortness of breath or swelling of the mouth or throat), call 911 or get medical care right away. In case of overdose, get medical help or call a Poison Control Center right away.

Section 42229-5 (42229-5)

HOW POTASSIUM IODIDE WORKS

Certain forms of iodine help your thyroid gland work right. Most people get the iodine they need from foods like iodized salt or fish. The thyroid can "store" or hold only a certain amount of iodine.

In a nuclear radiation emergency, radioactive iodine may be released in the air. This material may be breathed or swallowed. It may enter the thyroid gland and damage it. The damage would probably not show itself for years. Children are most likely to have thyroid damage.

If you take KI, it will block or reduce the chances that radioactive iodine will enter your thyroid gland.

Section 50565-1 (50565-1)

Carton Label - Principal Display Panel

NDC-50633-910-20

ThyroSafe ®

Potassium Iodide Tablets, USP, 65 mg

Thyroid blocking in a radiation emergency only

20 tablets, 65 milligrams each

Carton Label – Back panel

Potassium Iodide (KI) Tablets USP, 65 mg

Drug Facts
Active Ingredient (in each tablet)

Potassium Iodide 65 mg
Purpose

Thyroid blocking
Usehelps prevent radioactive iodine from getting into the thyroid gland during a nuclear radiation emergency. Use along with other emergency measures recommended by public officials.
Warnings

Allergy alert:
Iodine may cause an allergic reaction with 1 or more of the following symptoms:
  • shortness of breath or wheezing
  • swelling
  • skin rash
  • trouble breathing, speaking or swallowing
  • fever and joint pain
Do not useif you have
  • ever had an allergic reaction to iodine
  • nodular thyroid disease with heart disease
  • hypocomplementemic vasculitis
  • dermatitis herpetiformis
Stop use and ask a doctor if you haveif you have
  • allergic reaction. Get medical help right away if you have trouble breathing, speaking or swallowing; shortness of breath; wheezing; swelling of the mouth, tongue or throat; or rash.
  • irregular heart or chest pain. Get medical help right away.
  • swelling of the hands or feet, fever, or joint pain.
Keep out of reach of children.In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
  • use as directed by public officials in the event of a nuclear radiation emergency.
  • do not take more than 1 dose in 24 hours.
  • tablets can be whole or crushed and mixed in milk, baby formula, water, orange juice, flat soda like cola, or raspberry syrup.

The liquid mixture should be given to infants, young children, and others who cannot swallow tablets; see consumer package insert on how to make a liquid mixture.

adults over 18 years 2 tablets (whole or crushed) daily (130 mg)
children over 12 years to 18 years who weigh at least 150 pounds 2 tablets (whole or crushed) daily (130 mg)
children over 12 years to 18 years who weigh less than 150 pounds 1 tablet (whole or crushed) daily (65 mg)
children over 3 years to 12 years 1 tablet (whole or crushed) daily (65 mg)
children over 1 month to 3 years 1/2 tablet (crushed) 32.5 mg daily as directed in the consumer package insert
babies at birth to 1 month 16.25 mg daily as directed in consumer package insert
If pregnant, breastfeeding, have a baby up to 1 month of age, or have thyroid disease(except nodular thyroid disease with heart disease), take as directed above and contact a doctor as soon as possible
Section 51727-6 (51727-6)

Inactive ingredients

lactose, magnesium stearate, microcrystalline cellulose

Questions or comments?

call toll free 1-866-849-7672

Section 55105-1 (55105-1)

INDICATIONS

ThyroSafe® (Potassium Iodide Tablets, USP) is a thyroid blocking medicine that is used in a nuclear radiation emergency only.

Section 55106-9 (55106-9)

DESCRIPTION

Each white, round, cross-scored ThyroSafe® tablet contains 65 mg of potassium iodide.

Principal Display Panel Pack Label (Principal Display Panel - Pack Label)

Principal Display Panel 65 Mg Carton Label (Principal Display Panel - 65 mg Carton Label)

NDC-50633-910-20

ThyroSafe ®

Potassium Iodide Tablets, USP, 65 mg

Thyroid blocking in a radiation emergency only

20 tablets, 65 milligrams each

BTG International Inc.


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