SPL v1
SPL
SPL Set ID 46f5c653-eec2-4729-8aaa-79f2e188eac3
Route
ORAL
Published
Effective Date 2025-07-25
Document Type 34390-5 HUMAN OTC DRUG LABEL

Drug Facts

Composition & Product

Active Ingredients
Loperamide (2 mg) Dimethicone (125 mg)
Inactive Ingredients
Acesulfame Potassium Silicon Dioxide Croscarmellose Sodium Anhydrous Dibasic Calcium Phosphate Microcrystalline Cellulose Stearic Acid

Identifiers & Packaging

Pill Appearance
Imprint: L;II Shape: capsule Color: white Size: 17 mm Score: 2
Marketing Status
ANDA Active Since 2021-09-10

Description

Loperamide HCl, USP 2 mg Simethicone, USP 125 mg

Purpose

Anti-diarrheal Anti-gas


Medication Information

Purpose

Anti-diarrheal Anti-gas

Description

Loperamide HCl, USP 2 mg Simethicone, USP 125 mg

Uses

Relieves symptoms of diarrhea plus bloating, pressure and cramps, commonly referred to as gas

Purposes

Anti-diarrheal

Anti-gas

Warnings

Allergy alert: Do not use if you have ever had a rash or other allergic reaction to Loperamide HCl.

Heart alert: Taking more than directed can cause serious heart problems or death.

Directions
  • drink plenty of clear fluids to help prevent dehydration caused by diarrhea
  • take only on an empty stomach (1 hour before or 2 hours after a meal)
  • take with a full (8 oz.) glass of water
  • find right dose on chart below. If possible, use weight to dose; otherwise, use age.

    adults and children 12 years and over 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hours
    children 9-11 years (60-95 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours
    children 6-8 years (48-59 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 2 caplets in 24 hours
    children 2-5 years (34 to 47 lbs) ask a doctor
    children under 2 years (up to 33 lbs) do not use

Do Not Use
  • if you have bloody or black stool
  • if you have difficulty swallowing
Questions?

call toll-free 1-866-933-6337

Other Information
  • each caplet contains: calcium 155 mg, sodium 3 mg
  • store at 20-25°C (68-77°F)
  • protect from light
Inactive Ingredients

acesulfame potassium, anhydrous dicalcium phosphate, colloidal silicon dioxide, croscarmellose sodium, microcrystalline cellulose, stearic acid, vanilla flavor

Principal Display Panel

When Using This Product

tiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery.

Stop Use and Ask A Doctor If
  • symptoms get worse
  • diarrhea lasts for more than 2 days
  • you have difficulty swallowing the caplet
  • you get abdominal swelling or bulging. These may be signs of a serious condition.
Keep Out of Reach of Children

In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

If Pregnant Or Breast Feeding,

ask a health professional before use.

Ask A Doctor Before Use If You Are

taking a prescription drug. Loperamide may interact with certain prescription drugs.

Active Ingredients (in Each Caplet)

Loperamide HCl, USP 2 mg

Simethicone, USP 125 mg

Ask A Doctor Before Use If You Have 
  • fever
  • mucus in the stool
  • a history of liver disease
  • a history of abnormal heart rhythm

Structured Label Content

Uses

Relieves symptoms of diarrhea plus bloating, pressure and cramps, commonly referred to as gas

Purposes

Anti-diarrheal

Anti-gas

Warnings

Allergy alert: Do not use if you have ever had a rash or other allergic reaction to Loperamide HCl.

Heart alert: Taking more than directed can cause serious heart problems or death.

Directions
  • drink plenty of clear fluids to help prevent dehydration caused by diarrhea
  • take only on an empty stomach (1 hour before or 2 hours after a meal)
  • take with a full (8 oz.) glass of water
  • find right dose on chart below. If possible, use weight to dose; otherwise, use age.

    adults and children 12 years and over 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hours
    children 9-11 years (60-95 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours
    children 6-8 years (48-59 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 2 caplets in 24 hours
    children 2-5 years (34 to 47 lbs) ask a doctor
    children under 2 years (up to 33 lbs) do not use

Do Not Use (Do not use)
  • if you have bloody or black stool
  • if you have difficulty swallowing
Questions?

call toll-free 1-866-933-6337

Other Information (Other information)
  • each caplet contains: calcium 155 mg, sodium 3 mg
  • store at 20-25°C (68-77°F)
  • protect from light
Inactive Ingredients (Inactive ingredients)

acesulfame potassium, anhydrous dicalcium phosphate, colloidal silicon dioxide, croscarmellose sodium, microcrystalline cellulose, stearic acid, vanilla flavor

Principal Display Panel

When Using This Product (When using this product)

tiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery.

Stop Use and Ask A Doctor If (Stop use and ask a doctor if)
  • symptoms get worse
  • diarrhea lasts for more than 2 days
  • you have difficulty swallowing the caplet
  • you get abdominal swelling or bulging. These may be signs of a serious condition.
Keep Out of Reach of Children (Keep out of reach of children)

In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

If Pregnant Or Breast Feeding, (If pregnant or breast-feeding,)

ask a health professional before use.

Ask A Doctor Before Use If You Are (Ask a doctor before use if you are)

taking a prescription drug. Loperamide may interact with certain prescription drugs.

Active Ingredients (in Each Caplet) (Active Ingredients (in each caplet))

Loperamide HCl, USP 2 mg

Simethicone, USP 125 mg

Ask A Doctor Before Use If You Have  (Ask a doctor before use if you have )
  • fever
  • mucus in the stool
  • a history of liver disease
  • a history of abnormal heart rhythm

Advanced Ingredient Data


Raw Label Data

All Sections (JSON)