vanrafia - Medication Listings

Browse 1 medications by vanrafia. Open a product record to review strengths, dosage forms, label-backed details, and related navigation.

VANRAFIA ATRASENTAN
NOVARTIS PHARMACEUTICALS CORPORATION FDA Rx Only

VANRAFIA contains atrasentan, an endothelin type A (ET A ) receptor antagonist. The chemical name of atrasentan hydrochloride is (2 R , 3 R , 4 S )-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid hydrochloride. Atrasentan hydrochloride has a molecular weight of 547.09 g/mol, a molecular formula of C 29 H 38 N 2 O 6 HCl and the following structural formula. Atrasentan is a slightly hygroscopic white to off-white powder that is slightly soluble in water. VANRAFIA is available as a film-coated tablet for oral administration. Each VANRAFIA tablet contains 0.75 mg atrasentan (equivalent to 0.803 mg of atrasentan hydrochloride) and contains the following excipients: crospovidone, glyceryl dibehenate, hypromellose, lactose monohydrate, L-cysteine hydrochloride monohydrate, polyethylene glycol, and silicon dioxide. Atrasentan structural formula

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