synarel - Medication Listings
Browse 1 medications by synarel. Open a product record to review strengths, dosage forms, label-backed details, and related navigation.
SYNAREL (nafarelin acetate) Nasal Solution is intended for administration as a spray to the nasal mucosa. Nafarelin acetate, the active component of SYNAREL Nasal Solution, is a decapeptide with the chemical name: 5-oxo- L -prolyl- L -histidyl- L -tryptophyl- L -seryl- L -tyrosyl-3-(2-naphthyl)- D -alanyl- L -leucyl- L -arginyl- L -prolyl-glycinamide acetate. Nafarelin acetate is a synthetic analog of the naturally occurring gonadotropin-releasing hormone (GnRH). Nafarelin acetate has the following chemical structure: ∙ x CH 3 COOH ∙ y H 2 O (1 ⩽ x ⩽ 2; 2 ⩽ y ⩽ 8) SYNAREL Nasal Solution contains nafarelin acetate (2 mg/mL, content expressed as nafarelin base) in a solution of benzalkonium chloride, glacial acetic acid, sodium hydroxide or hydrochloric acid (to adjust pH), sorbitol, and purified water. After priming the pump unit for SYNAREL, each actuation of the unit delivers approximately 100 µL of the spray containing approximately 200 µg nafarelin base. The contents of one spray bottle are intended to deliver at least 60 sprays. Chemical Structure DESCRIPTION SYNAREL (nafarelin acetate) Nasal Solution is intended for administration as a spray to the nasal mucosa. Nafarelin acetate, the active component of SYNAREL Nasal Solution, is a decapeptide with the chemical name: 5-oxo- L -prolyl- L -histidyl- L -tryptophyl- L -seryl- L -tyrosyl-3-(2-naphthyl)- D -alanyl- L -leucyl- L -arginyl- L -prolyl-glycinamide acetate. Nafarelin acetate is a synthetic analog of the naturally occurring gonadotropin-releasing hormone (GnRH). Nafarelin acetate has the following chemical structure: ∙ x CH3COOH ∙ y H2O (1 ⩽ x ⩽ 2; 2 ⩽ y ⩽ 8) SYNAREL Nasal Solution contains nafarelin acetate (2 mg/mL, content expressed as nafarelin base) in a solution of benzalkonium chloride, glacial acetic acid, sodium hydroxide or hydrochloric acid (to adjust pH), sorbitol, and purified water. After priming the pump unit for SYNAREL, each actuation of the unit delivers approximately 100 µL of the spray containing approximately 200 µg nafarelin base. The contents of one spray bottle are intended to deliver at least 60 sprays. Chemical Structure
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