somatuline depot - Medication Listings

SOMATULINE DEPOT (lanreotide) Injection 60 mg/0.2 mL, 90 mg/0.3 mL, and 120 mg/0.5 mL is a prolonged-release formulation for deep subcutaneous injection. It contains the drug substance lanreotide acetate, a synthetic octapeptide with a biological activity similar to naturally occurring somatostatin, water for injection and acetic acid (for pH adjustment). SOMATULINE DEPOT is available as sterile, ready-to-use, single-dose prefilled syringes containing lanreotide acetate supersaturated bulk solution of 24.6% w/w lanreotide base. Each syringe contains: SOMATULINE DEPOT 60 mg/0.2 mL SOMATULINE DEPOT 90 mg/0.3 mL SOMATULINE DEPOT 120 mg/0.5 mL Lanreotide acetate 77.9 mg 113.6 mg 149.4 mg Acetic Acid q.s. q.s. q.s. Water for injection 186.6 mg 272.3 mg 357.8 mg Total Weight 266 mg 388 mg 510 mg Lanreotide acetate is a synthetic cyclical octapeptide analog of the natural hormone, somatostatin. Lanreotide acetate is chemically known as [cyclo S-S]-3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide, acetate salt. Its molecular weight is 1096.34 (base) and its amino acid sequence is: The SOMATULINE DEPOT in the prefilled syringe is a white to pale yellow, semi-solid formulation. Chemical Structure