prilosec - Medication Listings

The active ingredient in PRILOSEC (omeprazole magnesium) for delayed-release oral suspension, is 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1 H -benzimidazole, magnesium salt (2:1). Omeprazole magnesium is a white to off white powder with a melting point with degradation at 200°C. The salt is slightly soluble (0.25 mg/mL) in water at 25°C, and it is soluble in methanol. The half-life is highly pH dependent. The empirical formula for omeprazole magnesium is (C 17 H 18 N 3 O 3 S) 2 Mg, the molecular weight is 713.12 and the structural formula is: Each packet of PRILOSEC for delayed-release oral suspension contains either 2.5 mg or 10 mg of omeprazole (equivalent to 2.8 mg or 11.2 mg of omeprazole magnesium trihydrate), in the form of enteric-coated granules with the following inactive ingredients: glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer C, polysorbate, sugar spheres, talc, and triethyl citrate, and also inactive granules. The inactive granules are composed of the following ingredients: citric acid, crospovidone, dextrose, hydroxypropyl cellulose, iron oxide and xanthan gum. The omeprazole granules and inactive granules are constituted with water to form a suspension and are given by oral, nasogastric, or direct gastric administration. omeprazole magnesium structural formula