fluvastatin sodium - Medication Listings

Fluvastatin sodium is a water-soluble cholesterol lowering agent which acts through the inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Fluvastatin sodium is Sodium (±)-(3 R *,5 S *,6 E )-7-[3-( p -fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxy-6-heptenoate. The molecular formula of fluvastatin sodium is C 24 H 25 FNNaO 4 , its molecular weight is 433.45 and its structural formula is: This molecular entity is the first entirely synthetic HMG-CoA reductase inhibitor, and is in part structurally distinct from the fungal derivatives of this therapeutic class. Fluvastatin sodium, USP is an off-white to yellow, hygroscopic powder soluble in water, ethanol and methanol. Fluvastatin is supplied as capsules containing fluvastatin sodium, equivalent to 20 mg or 40 mg of fluvastatin, for oral administration. Active ingredient: fluvastatin sodium Inactive ingredients in capsules: corn starch, crospovidone, gelatin, magnesium stearate, red iron oxide, sodium lauryl sulfate, talc, titanium dioxide and yellow iron oxide. In addition, the black imprinting ink for the 20 mg and 40 mg capsules contains ammonium hydroxide, black iron oxide, propylene glycol and shellac glaze. Fluvastatin Structural Formula

Fluvastatin sodium inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Fluvastatin sodium is [R*,S*-(E)]-(±)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]- 3,5-dihydroxy-6-heptenoic acid, monosodium salt. The empirical formula of fluvastatin sodium is C24H25FNO4•Na, its molecular weight is 433.46 g/mol and its structural formula is: Fluvastatin sodium, USP is a white to pale yellow, brownish-pale yellow, or reddish-pale yellow, hygroscopic powder soluble in alcohol, in methanol, and in water. Fluvastatin sodium extended-release tablets are supplied as extended-release tablets containing fluvastatin sodium, equivalent to 80 mg of fluvastatin, for oral use. Fluvastatin sodium extended-release tablets contain the following inactive ingredients: glycerol dibehenate, pregelatinized starch, hypromellose, potassium bicarbonate, magnesium stearate, polyvinyl alcohol, titanium dioxide, talc, lecithin (soya), yellow iron oxide non-irradiated, shellac glaze (modified) in SD-45, isopropyl alcohol, black iron oxide non-irradiated, N-butyl alcohol, propylene glycol, ammonium hydroxide. fluvastatin-sodium-structure

Fluvastatin sodium, USP inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Fluvastatin sodium, USP is [ R * , S * -( E )]-(±)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1 H- indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, monosodium salt. The structural formula is: C 24 H 25 FNNaO 4 M.W. 433.46 Fluvastatin sodium, USP (hydrated form) is a white to pale yellow, brownish-pale yellow, or reddish-pale yellow hygroscopic powder soluble in water, ethanol and methanol. Fluvastatin Sodium Extended-Release Tablets contains 84.24 mg of fluvastatin sodium, USP (hydrated form), equivalent to 80 mg of fluvastatin, for oral use. Fluvastatin sodium extended-release tablets contain the following inactive ingredients: crospovidone, hydroxyethyl cellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol partially hydrolyzed, talc, and titanium dioxide. fluvastatin sodium structural formula