carbocaine - Medication Listings

CARBOCAINE (mepivacaine hydrochloride), a tertiary amine used as a local anesthetic, is 1-methyl-2', 6' - pipecoloxylidide monohydrochloride with the following structural formula: C 15 H 22 N 2 0.HCl M.W. 282.81 It is a white, crystalline, odorless powder soluble in water, but very resistant to both acid and alkaline hydrolysis. NEO-COBEFRIN, a sympathomimetic amine used as a vasoconstrictor in local anesthetic solution, is (-)- -(1-Aminoethyl)-3, 4-dihydroxybenzyl alcohol with the following structural formula: C 9 H 13 NO 3 M.W. 183.21 It is a white or buff-colored crystalline solid, freely soluble in aqueous solutions of mineral acids, but practically insoluble in water. DENTAL CARTRIDGES MAY NOT BE AUTOCLAVED. CARBOCAINE 3% (30 mg/mL) injection and CARBOCAINE 2% (20 mg/mL) with NEO-COBEFRIN 1:20,000 injection are sterile solutions for injection. COMPOSITION: CARTRIDGE Each mL contains: 2% 3% Mepivacaine hydrochloride 20 mg 30 mg Levonordefrin 0.05mg - Sodium chloride 4 mg 6 mg Potassium metabisulfite 1.2 mg - Edetate disodium 0.25mg - Sodium hydroxide q.s. ad pH Hydrochloric acid 0.5 mg - Water for injections qs. ad. 1 mL 1 mL The pH of the 2% cartridge solution is adjusted between 3.3 and 5.5 with NaOH. The pH of the 3% cartridge solution is adjusted between 4.5 and 6.8 with NaOH. Chemical Structure Chemical Structure Symbol