brimonidine tartrate/timolol maleate - Medication Listings
Browse 2 medications by brimonidine tartrate/timolol maleate. Open a product record to review strengths, dosage forms, label-backed details, and related navigation.
Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution 0.2%/0.5%, sterile, is a relatively selective alpha-2 adrenergic receptor agonist with a non-selective beta-adrenergic receptor inhibitor (topical intraocular pressure lowering agent). The structural formulae are: Brimonidine tartrate: 5-bromo-6-(2-imidazolidinylideneamino) quinoxaline L-tartrate; MW= 442.22 Timolol maleate: (-)-1-( tert -butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)-oxy]-2-propanol maleate (1:1) (salt); MW= 432.49 as the maleate salt In solution, Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution 0.2%/0.5% has a clear, greenish-yellow color. It has an osmolality of 260-330 mOsmol/kg and a pH during its shelf life of 6.5-7.3. Brimonidine tartrate appears as a white, or slightly yellowish, or slightly brownish powder and is soluble in water and practically insoluble in anhydrous ethanol and toluene. Timolol maleate appears as a white to practically white powder and is soluble in water, methanol, and alcohol, sparingly soluble in chloroform and propylene glycol and insoluble in ether and cyclohexane. Each mL of Brimonidine Tartrate/Timolol Maleate Ophthalmic Solutioncontains the active ingredients brimonidine tartrate 0.2% and timolol 0.5% with the inactive ingredients benzalkonium chloride 0.005%; sodium phosphate, monobasic; sodium phosphate, dibasic; water for injection; and hydrochloric acid and/or sodium hydroxide to adjust pH. structure structure1
Brimonidine tartrate/timolol maleate ophthalmic solution 0.2%/0.5%, sterile, is a relatively selective alpha-2 adrenergic receptor agonist with a non-selective beta-adrenergic receptor inhibitor (topical intraocular pressure lowering agent). The structural formulae are: Brimonidine tartrate: 5-bromo-6-(2-imidazolidinylideneamino) quinoxaline L-tartrate; MW= 442.24 Timolol maleate: (-)-1-( tert -butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)-oxy]-2-propanol maleate (1:1) (salt); MW= 432.50 as the maleate salt In solution, brimonidine tartrate/timolol maleate ophthalmic solution 0.2%/0.5% has a clear, greenish-yellow color. It has an osmolality of 260 to 330 mOsmol/kg and a pH during its shelf life of 6.5 to 7.3. Brimonidine tartrate appears as an off-white, or white to pale-yellow powder and is soluble in both water (1.5 mg/mL) and in the product vehicle (3 mg/mL) at pH 7.2. Timolol maleate appears as a white, odorless, crystalline powder and is soluble in water, methanol, and alcohol. Each mL of brimonidine tartrate/timolol maleate ophthalmic solution contains the active ingredients brimonidine tartrate 0.2% and timolol 0.5% with the inactive ingredients benzalkonium chloride 0.005%; dibasic sodium phosphate USP, monobasic sodium phosphate USP, water for injection. Hydrochloric acid and/or sodium hydroxide to adjust pH. Brimonidine tartrate chemical structure Timolol maleate chemical structure
About brimonidine tartrate/timolol maleate Medications
This collection groups medications in our database that are associated with brimonidine tartrate/timolol maleate. It currently includes 2 matching listings. Open a drug detail page to review dosage forms, strengths, ingredients, labeling, and related brand or generic context.
How to Use This Page
Use these results to move into a specific drug detail page, then follow related brand, generic, manufacturer, or substance links for broader exploration.
Safety Information
Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. The information provided on this page is for educational purposes only and does not constitute medical advice.